KIF1C and LAMC3

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		KIF1C	LAMC3
Description		kinesin family member 1C	laminin subunit gamma 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Golgi Apparatus Cytoskeleton Kinesin Complex Microtubule Axon Dendrite Axon Cytoplasm	Extracellular Region Basement Membrane Membrane Extracellular Matrix
	Molecular Function	Nucleotide Binding RNA Binding Cytoskeletal Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity ATP Hydrolysis Activity	Structural Molecule Activity
	Biological Process	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Vesicle-mediated Transport Anterograde Neuronal Dense Core Vesicle Transport Retrograde Neuronal Dense Core Vesicle Transport	Cell Morphogenesis Cell Adhesion Visual Perception Astrocyte Development Retina Development In Camera-type Eye
Pathways		COPI-dependent Golgi-to-ER retrograde traffic Kinesins	Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions MET activates PTK2 signaling Attachment of bacteria to epithelial cells Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC) Developmental Lineage of Pancreatic Ductal Cells
Drugs
Diseases
GWAS		Mean spheric corpuscular volume ( 32888494) Reticulocyte count ( 32888494) Spleen volume ( 34128465)	Alcohol consumption (max-drinks) ( 29460428) Deep ovarian and/or rectovaginal disease with dense adhesions ( 28333195) Degraded stimulus continuous performance test score ( 31596458) Endometriosis ( 28333195) Oral cavity and pharyngeal cancer ( 27749845) Oral cavity cancer ( 27749845) Smoking status (heavy vs never) ( 26423011)
Interacting Genes		10 interacting genes: CSNK2A1 CSNK2A2 LAMC3 PTPN21 RNF10 TSC1 YWHAB YWHAE YWHAG YWHAZ	20 interacting genes: ANXA5 CFB CRP CSNK2A2 CWC25 CYP2E1 EPB41L4B FRAT1 HP KIF1C LGMN NR1H2 PELI2 POT1 RPL35 SERPINA3 SLC43A3 TF YTHDC1 ZNF160
Entrez ID		10749	10319
HPRD ID		04342	05069
Ensembl ID		ENSG00000129250	ENSG00000050555
Uniprot IDs		O43896	Q8N2D6 Q9Y6N6
PDB IDs		2G1L 9KO8
Enriched GO Terms of Interacting Partners?		Phosphoserine Residue Binding Protein Sequestering Activity Protein Targeting Protein Kinase CK2 Complex Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of TORC1 Signaling TORC1 Signaling Protein Domain Specific Binding Cerebral Cortex Development TOR Signaling Negative Regulation Of TOR Signaling Regulation Of TORC1 Signaling Melanosome Regulation Of Protein Stability Focal Adhesion Regulation Of Protein Localization Regulation Of TOR Signaling Cellular Response To Stress PcG Protein Complex Cellular Response To Starvation Regulation Of Macroautophagy Phosphoprotein Binding Hsp90 Protein Binding Response To Starvation Protein Catabolic Process Protein Stabilization Protein Phosphatase Inhibitor Activity Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Translational Initiation Negative Regulation Of Protein Localization To Nucleus Cellular Response To Glucose Starvation Cellular Response To Nutrient Levels Regulation Of Signal Transduction Signal Transduction Establishment Of Protein Localization Negative Regulation Of Proteasomal Protein Catabolic Process Memory T Cell Differentiation Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of TORC1 Signaling Negative Regulation Of Intracellular Signal Transduction Cadherin Binding Hippocampus Development Regulation Of Cell Communication Regulation Of Signaling Regulation Of Chromosome Separation Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Negative Regulation Of Catabolic Process Regulation Of Autophagy	Acute-phase Response Blood Microparticle Acute Inflammatory Response Response To Bacterium Negative Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of Lipid Storage
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