CGRRF1 and CD72

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CGRRF1	CD72
Description		cell growth regulator with ring finger domain 1	CD72 molecule
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Endoplasmic Reticulum	Plasma Membrane Membrane
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Transmembrane Signaling Receptor Activity Signaling Receptor Binding Protein Binding Carbohydrate Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Growth Regulation Of Cell Cycle	Cell Adhesion Negative Regulation Of B Cell Receptor Signaling Pathway
Pathways			Other semaphorin interactions
Drugs
Diseases
GWAS		Dental caries ( 23259602) Monobrow thickness ( 26926045) Night sleep phenotypes ( 27126917)	Blood protein levels ( 30072576) Electroencephalogram traits ( 25387704)
Interacting Genes		32 interacting genes: AGR3 BET1 CD72 CDIPT CREB3 CYB5B FAM241B FAXDC2 FFAR2 GPR151 GPR152 JAGN1 KLRC1 LAPTM4B LNPEP MARCHF5 MTIF3 PEX10 PGAP2 RHBDD1 SCAMP4 SLC30A3 SLC30A8 SUSD3 TMEM140 TMEM187 TMEM31 TMEM97 TPRG1 UBE2U YIPF6 ZFPL1	22 interacting genes: ATP6AP2 BIK BLNK CD5 CGRRF1 CLDN7 CREB3L1 GPR152 GRAMD1C GRB2 LHFPL5 LMNA LRRC25 LSMEM2 LYN MS4A3 MS4A7 NRG1 PTPN6 SEMA4D SPACA1 SYK
Entrez ID		10668	971
HPRD ID		09366	00118
Ensembl ID		ENSG00000100532	ENSG00000137101
Uniprot IDs		Q99675	P21854 Q5TLG3
PDB IDs		2EA5
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Zinc Ion Import Into Organelle	B Cell Receptor Signaling Pathway T Cell Costimulation Membrane Antigen Receptor-mediated Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of T Cell Activation Positive Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of Cell Adhesion Phosphotyrosine Residue Binding Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cell Adhesion Mediated By Integrin SH2 Domain Binding Peptidyl-tyrosine Phosphorylation Regulation Of Cell Adhesion Plasma Membrane Positive Regulation Of Cell-cell Adhesion Positive Regulation Of Lymphocyte Activation Immune Response-activating Signaling Pathway Phosphorylation-dependent Protein Binding Negative Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Cell Activation Regulation Of T Cell Activation Regulation Of Leukocyte Cell-cell Adhesion Neutrophil Activation Involved In Immune Response Regulation Of MAPK Cascade Negative Regulation Of Immune Response Immune Response-regulating Signaling Pathway Activation Of Immune Response Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Lymphocyte Activation Regulation Of Mast Cell Activation Stimulatory C-type Lectin Receptor Signaling Pathway Cellular Response To Lectin Phospholipase Binding Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Cell Adhesion Mediated By Integrin Positive Regulation Of Cellular Component Biogenesis Regulation Of Lymphocyte Activation Regulation Of Cell-cell Adhesion SH3 Domain Binding Negative Regulation Of Defense Response Regulation Of ERK1 And ERK2 Cascade Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of B Cell Receptor Signaling Pathway Fc-epsilon Receptor Signaling Pathway Chemorepellent Activity Ephrin Receptor Binding Neutrophil Activation
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