CGRRF1 and SLC30A3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CGRRF1	SLC30A3
Description		cell growth regulator with ring finger domain 1	solute carrier family 30 member 3
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Endoplasmic Reticulum	Cytoplasm Lysosome Lysosomal Membrane Endosome Late Endosome Plasma Membrane Synaptic Vesicle Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Late Endosome Membrane Neuron Projection Synapse Hippocampal Mossy Fiber Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse Microvesicle
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Zinc Ion Transmembrane Transporter Activity Protein Binding Monoatomic Cation Transmembrane Transporter Activity Antiporter Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Growth Regulation Of Cell Cycle	Monoatomic Ion Transport Monoatomic Cation Transport Zinc Ion Transport Response To Zinc Ion Positive Regulation Of Transport Transmembrane Transport Zinc Ion Import Into Organelle Zinc Ion Transmembrane Transport Zinc Ion Import Into Synaptic Vesicle Zinc Ion Import Into Lysosome
Pathways			Zinc efflux and compartmentalization by the SLC30 family
Drugs
Diseases
GWAS		Dental caries ( 23259602) Monobrow thickness ( 26926045) Night sleep phenotypes ( 27126917)	Metabolite levels ( 23823483)
Interacting Genes		32 interacting genes: AGR3 BET1 CD72 CDIPT CREB3 CYB5B FAM241B FAXDC2 FFAR2 GPR151 GPR152 JAGN1 KLRC1 LAPTM4B LNPEP MARCHF5 MTIF3 PEX10 PGAP2 RHBDD1 SCAMP4 SLC30A3 SLC30A8 SUSD3 TMEM140 TMEM187 TMEM31 TMEM97 TPRG1 UBE2U YIPF6 ZFPL1	33 interacting genes: AP3B1 AP3D1 AP3S1 AQP6 CD40 CD79A CGRRF1 CYB5R3 DNAJC5 ELOVL4 FCRL3 FKBP7 GJA8 GOLM1 GPR152 GPR42 GPX8 HSD17B13 LMNA NAALADL2 RETREG3 RNF19B RTN3 SAR1A SCN3B SGPL1 SLC10A6 SLC18A1 SLC30A8 SLC34A2 SLC35H1 TMEM14B TMEM242
Entrez ID		10668	7781
HPRD ID		09366	11924
Ensembl ID		ENSG00000100532	ENSG00000115194
Uniprot IDs		Q99675	B4DXX8 Q99726
PDB IDs		2EA5	8XN1
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Zinc Ion Import Into Organelle	Membrane Clathrin-coated Vesicle Cargo Loading, AP-3-mediated Vesicle Cargo Loading AP-3 Adaptor Complex Anterograde Synaptic Vesicle Transport Melanosome Assembly Platelet Dense Granule Organization Membrane Coat Positive Regulation Of NK T Cell Differentiation Synaptic Vesicle Transport Synaptic Vesicle Coating Vesicle Coating Melanosome Organization Pigment Granule Organization Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Regulation Of NK T Cell Differentiation Anterograde Axonal Transport Endoplasmic Reticulum Vesicle Transport Along Microtubule Zinc Ion Import Into Organelle Vesicle Cytoskeletal Trafficking Transmembrane Transport Axon Cytoplasm Axonal Transport Secretory Granule Organization Protein Binding Synaptic Vesicle Recycling Axo-dendritic Transport Golgi To Vacuole Transport Organelle Transport Along Microtubule Endoplasmic Reticulum Membrane Endoplasmic Reticulum Tubular Network Organization Inorganic Cation Transmembrane Transport Presynapse Establishment Of Vesicle Localization Zinc Ion Transmembrane Transport Zinc Ion Transport Monoatomic Ion Transport Vesicle Localization Intracellular Zinc Ion Homeostasis Establishment Of Organelle Localization Nitrate Transmembrane Transporter Activity Inorganic Ion Transmembrane Transport Sphinganine-1-phosphate Aldolase Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport
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