CGRRF1 and TPRG1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CGRRF1	TPRG1
Description		cell growth regulator with ring finger domain 1	tumor protein p63 regulated 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Endoplasmic Reticulum	Cytoplasm
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Growth Regulation Of Cell Cycle
Pathways
Drugs
Diseases
GWAS		Dental caries ( 23259602) Monobrow thickness ( 26926045) Night sleep phenotypes ( 27126917)	Allergic rhinitis ( 30013184) Asthma ( 31959851) Axial length ( 24144296) Cutaneous squamous cell carcinoma ( 32041948) Femur bone mineral density x serum urate levels interaction ( 34046847) Hair color ( 26926045) Squamous cell carcinoma ( 26829030)
Interacting Genes		32 interacting genes: AGR3 BET1 CD72 CDIPT CREB3 CYB5B FAM241B FAXDC2 FFAR2 GPR151 GPR152 JAGN1 KLRC1 LAPTM4B LNPEP MARCHF5 MTIF3 PEX10 PGAP2 RHBDD1 SCAMP4 SLC30A3 SLC30A8 SUSD3 TMEM140 TMEM187 TMEM31 TMEM97 TPRG1 UBE2U YIPF6 ZFPL1	19 interacting genes: APOC1 APOC2 APOC4 AQP6 CGRRF1 CIDEB EBAG9 FCER1G HSD17B11 HSD17B13 REEP4 RETREG3 RHBDD2 SCN3B SLC10A6 SLC35H1 SLC71A2 TMEM120A TMX2
Entrez ID		10668	285386
HPRD ID		09366	13451
Ensembl ID		ENSG00000100532	ENSG00000188001
Uniprot IDs		Q99675	Q6ZUI0
PDB IDs		2EA5
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Zinc Ion Import Into Organelle	High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Steroid Dehydrogenase Activity Acylglycerol Homeostasis Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Triglyceride Homeostasis Regulation Of Triglyceride Metabolic Process Endoplasmic Reticulum Lipid Transport Regulation Of Phospholipid Catabolic Process Lipase Inhibitor Activity Organic Hydroxy Compound Transport Very-low-density Lipoprotein Particle Assembly Chylomicron Phospholipid Efflux Lipid Droplet Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Negative Regulation Of Lipoprotein Particle Clearance Negative Regulation Of Cholesterol Transport Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Plasma Lipoprotein Particle Assembly Protein-lipid Complex Assembly Regulation Of Lipid Metabolic Process Plasma Lipoprotein Particle Clearance Organophosphate Ester Transport Cholesterol Efflux Negative Regulation Of Receptor-mediated Endocytosis Lipoprotein Metabolic Process Lipid Storage Regulation Of Phospholipid Metabolic Process Plasma Lipoprotein Particle Remodeling Lipid Homeostasis Protein-containing Complex Remodeling Negative Regulation Of Lipid Transport Negative Regulation Of Phosphatidylcholine Catabolic Process Nitrate Transmembrane Transporter Activity Transmembrane Transport IgE Receptor Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport Regulation Of Lipid Biosynthetic Process Regulation Of Fatty Acid Biosynthetic Process Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Regulation Of Lipid Catabolic Process Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling PH-gated Chloride Channel Activity Nitrate Transmembrane Transport
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