CGRRF1 and GPR151

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CGRRF1	GPR151
Description		cell growth regulator with ring finger domain 1	G protein-coupled receptor 151
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Endoplasmic Reticulum	Plasma Membrane Membrane Synaptic Vesicle Membrane Presynaptic Membrane Cholinergic Synapse
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding	G Protein-coupled Receptor Activity Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell Growth Regulation Of Cell Cycle	Response To Ischemia Signal Transduction G Protein-coupled Receptor Signaling Pathway Response To Acidic PH Positive Regulation Of Immune Response Regulation Of Synaptic Vesicle Exocytosis
Pathways
Drugs
Diseases
GWAS		Dental caries ( 23259602) Monobrow thickness ( 26926045) Night sleep phenotypes ( 27126917)	Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		32 interacting genes: AGR3 BET1 CD72 CDIPT CREB3 CYB5B FAM241B FAXDC2 FFAR2 GPR151 GPR152 JAGN1 KLRC1 LAPTM4B LNPEP MARCHF5 MTIF3 PEX10 PGAP2 RHBDD1 SCAMP4 SLC30A3 SLC30A8 SUSD3 TMEM140 TMEM187 TMEM31 TMEM97 TPRG1 UBE2U YIPF6 ZFPL1	42 interacting genes: APOD AQP6 ARL6IP1 BCL2L2 C1GALT1 CD300C CDIPT CERS4 CGRRF1 CREB3L1 CYBC1 EFNA5 ERGIC3 FAM209A GAL GJA8 GPR152 GPX8 IGFBP5 KEAP1 LAT MANBAL NRM PGRMC2 PLP2 SACM1L SCN3B SHISAL1 SLC10A1 SLC10A6 SLC18A1 SLC18A2 SLC41A2 SSMEM1 STX8 TIMMDC1 TMBIM6 TMEM179B TMEM239 TMEM31 TRARG1 UNC93A
Entrez ID		10668	134391
HPRD ID		09366	17065
Ensembl ID		ENSG00000100532	ENSG00000173250
Uniprot IDs		Q99675	Q8TDV0
PDB IDs		2EA5
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Zinc Ion Import Into Organelle	Membrane Endoplasmic Reticulum Aminergic Neurotransmitter Loading Into Synaptic Vesicle Transmembrane Transport Serotonin:sodium:chloride Symporter Activity Monoamine:proton Antiporter Activity Monoatomic Ion Transport Bile Acid:sodium Symporter Activity Clathrin-sculpted Monoamine Transport Vesicle Membrane Neurotransmitter Loading Into Synaptic Vesicle Endoplasmic Reticulum Membrane Serotonin Uptake Monoamine Transmembrane Transporter Activity Amine Transport Monoatomic Cation Transport Serotonin Transport Protein Binding Organic Hydroxy Compound Transport
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