GPR151 and GAL

Number of citations of the paper that reports this interaction (PubMedID 15111018)
0

Data Source:
HPRD (in vitro)

		GPR151	GAL
Description		G protein-coupled receptor 151	galanin and GMAP prepropeptide
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Synaptic Vesicle Membrane Presynaptic Membrane Cholinergic Synapse	Extracellular Region Extracellular Space Secretory Granule Neuronal Cell Body
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Identical Protein Binding	Galanin Receptor Activity Hormone Activity Neuropeptide Hormone Activity Protein Binding Galanin Receptor Binding Type 1 Galanin Receptor Binding Type 2 Galanin Receptor Binding Type 3 Galanin Receptor Binding
	Biological Process	Response To Ischemia Signal Transduction G Protein-coupled Receptor Signaling Pathway Response To Acidic PH Positive Regulation Of Immune Response Regulation Of Synaptic Vesicle Exocytosis	Neuropeptide Signaling Pathway Nervous System Development Feeding Behavior Negative Regulation Of Cell Population Proliferation Response To Xenobiotic Stimulus Protein Kinase A Signaling Insulin Secretion Regulation Of Glucocorticoid Metabolic Process Response To Insulin Response To Immobilization Stress Positive Regulation Of Apoptotic Process Response To Estrogen Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Lymphocyte Proliferation Positive Regulation Of Cortisol Secretion Positive Regulation Of Timing Of Catagen Parental Behavior Positive Regulation Of Large Conductance Calcium-activated Potassium Channel Activity
Pathways			Peptide ligand-binding receptors G alpha (i) signalling events
Drugs
Diseases
GWAS		Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Femoral neck section modulus ( 30888730) Height ( 28552196) Serum metabolite levels ( 33031748)
Interacting Genes		42 interacting genes: APOD AQP6 ARL6IP1 BCL2L2 C1GALT1 CD300C CDIPT CERS4 CGRRF1 CREB3L1 CYBC1 EFNA5 ERGIC3 FAM209A GAL GJA8 GPR152 GPX8 IGFBP5 KEAP1 LAT MANBAL NRM PGRMC2 PLP2 SACM1L SCN3B SHISAL1 SLC10A1 SLC10A6 SLC18A1 SLC18A2 SLC41A2 SSMEM1 STX8 TIMMDC1 TMBIM6 TMEM179B TMEM239 TMEM31 TRARG1 UNC93A	7 interacting genes: ASPH GALR1 GALR2 GPR151 SGTA UBQLN1 UBQLN2
Entrez ID		134391	51083
HPRD ID		17065	00658
Ensembl ID		ENSG00000173250	ENSG00000069482
Uniprot IDs		Q8TDV0	P22466
PDB IDs			7S3O 7S3Q 7S3R 7WQ3 7WQ4 7XBD 7XJJ 7XJK 8DHZ 8DJ4
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Aminergic Neurotransmitter Loading Into Synaptic Vesicle Transmembrane Transport Serotonin:sodium:chloride Symporter Activity Monoamine:proton Antiporter Activity Monoatomic Ion Transport Bile Acid:sodium Symporter Activity Clathrin-sculpted Monoamine Transport Vesicle Membrane Neurotransmitter Loading Into Synaptic Vesicle Endoplasmic Reticulum Membrane Serotonin Uptake Monoamine Transmembrane Transporter Activity Amine Transport Monoatomic Cation Transport Serotonin Transport Protein Binding Organic Hydroxy Compound Transport	Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Proteolysis Galanin Receptor Activity Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Regulation Of Proteolysis Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Cytosolic Calcium Ion Concentration Neuropeptide Binding Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Peptide Hormone Binding Response To Endoplasmic Reticulum Stress Polyubiquitin Modification-dependent Protein Binding Regulation Of Transport Positive Regulation Of Protein Metabolic Process Positive Regulation Of Macromolecule Metabolic Process G Protein-coupled Receptor Activity Regulation Of Protein Catabolic Process Positive Regulation Of Metabolic Process Galanin-activated Signaling Pathway Negative Regulation Of Store-operated Calcium Channel Activity Regulation Of Transmembrane Transporter Activity Regulation Of Monoatomic Ion Transmembrane Transporter Activity Autophagosome Autophagosome Assembly Proteasomal Protein Catabolic Process Neuropeptide Signaling Pathway Autophagosome Organization Peptidyl-aspartic Acid 3-dioxygenase Activity TRC Complex Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of Cellular Response To Stress Positive Regulation Of Catabolic Process Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Protein Catabolic Process Regulation Of Calcium Ion Transmembrane Transport Membrane Positive Regulation Of Cortisol Secretion BAT3 Complex Binding Negative Regulation Of Clathrin-dependent Endocytosis Regulation Of Protein Metabolic Process Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Plasma Membrane Activation Of Store-operated Calcium Channel Activity Proteolysis Involved In Protein Catabolic Process
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