GPR151 and TMEM179B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GPR151	TMEM179B
Description		G protein-coupled receptor 151	transmembrane protein 179B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Synaptic Vesicle Membrane Presynaptic Membrane Cholinergic Synapse	Nucleolus Plasma Membrane Membrane Nuclear Speck Secretory Granule Membrane Azurophil Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Response To Ischemia Signal Transduction G Protein-coupled Receptor Signaling Pathway Response To Acidic PH Positive Regulation Of Immune Response Regulation Of Synaptic Vesicle Exocytosis
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		42 interacting genes: APOD AQP6 ARL6IP1 BCL2L2 C1GALT1 CD300C CDIPT CERS4 CGRRF1 CREB3L1 CYBC1 EFNA5 ERGIC3 FAM209A GAL GJA8 GPR152 GPX8 IGFBP5 KEAP1 LAT MANBAL NRM PGRMC2 PLP2 SACM1L SCN3B SHISAL1 SLC10A1 SLC10A6 SLC18A1 SLC18A2 SLC41A2 SSMEM1 STX8 TIMMDC1 TMBIM6 TMEM179B TMEM239 TMEM31 TRARG1 UNC93A	47 interacting genes: ADIPOQ BTN2A2 C1QL4 C2CD2L C3orf52 CCDC167 CCL3L3 CCL4 CCL4L2 CD68 CLCA4 CLCN7 CLDN1 CLDN6 CTXN3 CYB561 DERL3 ERGIC3 FAM163A FATE1 FCER1G FXYD3 GALNT15 GKN1 GPR151 GUCA2A IGFBP5 KRTAP12-2 KTN1 LRP10 LYG1 MARCHF2 MFSD6 PLN SERP2 SLC1A1 SLC22A1 SLC52A1 SLC61A1 STX8 TM4SF19 TMEM14A TMEM236 TMEM237 TMEM242 TMEM47 TRARG1
Entrez ID		134391	374395
HPRD ID		17065	14186
Ensembl ID		ENSG00000173250	ENSG00000185475
Uniprot IDs		Q8TDV0	G3V185 Q7Z7N9
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Aminergic Neurotransmitter Loading Into Synaptic Vesicle Transmembrane Transport Serotonin:sodium:chloride Symporter Activity Monoamine:proton Antiporter Activity Monoatomic Ion Transport Bile Acid:sodium Symporter Activity Clathrin-sculpted Monoamine Transport Vesicle Membrane Neurotransmitter Loading Into Synaptic Vesicle Endoplasmic Reticulum Membrane Serotonin Uptake Monoamine Transmembrane Transporter Activity Amine Transport Monoatomic Cation Transport Serotonin Transport Protein Binding Organic Hydroxy Compound Transport	Membrane Inorganic Anion Transport
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