SNX18

Gene Name		sorting nexin 18
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endosome Endosome Membrane Cytoplasmic Membrane-bounded Vesicle Clathrin-coated Vesicle Growth Cone Cytoplasmic Vesicle Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Neuronal Cell Body Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding
	Biological Process	Mitotic Cytokinesis Intracellular Protein Transport Endocytosis Mitotic Nuclear Division Vesicle Organization Endosomal Transport Cleavage Furrow Formation Positive Regulation Of GTPase Activity
Pathways
Drugs
Diseases
GWAS		Immune response to smallpox vaccine (IL-6) ( 22542470)
Protein-protein Interactions		2 interactors: SOS1 SOS2
Entrez ID		112574
HPRD ID		15407
Ensembl ID		ENSG00000178996
Uniprot IDs		Q96RF0
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Small GTPase Mediated Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Positive Regulation Of Rho GTPase Activity Regulation Of Rho GTPase Activity Regulation Of Rho Protein Signal Transduction Apoptotic Signaling Pathway Axon Guidance Positive Regulation Of Ras GTPase Activity Axonogenesis Regulation Of Ras GTPase Activity Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Response To Growth Factor Chemotaxis Positive Regulation Of Cell Death Small GTPase Mediated Signal Transduction Neuron Projection Morphogenesis Regulation Of Ras Protein Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Morphogenesis Involved In Differentiation Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Regulation Of GTPase Activity Positive Regulation Of Intracellular Signal Transduction Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuron Development Apoptotic Process Programmed Cell Death Positive Regulation Of ERBB Signaling Pathway Positive Regulation Of Hydrolase Activity Cell Death Death Cell Morphogenesis Neuron Differentiation Cell Projection Organization Locomotion Positive Regulation Of Signal Transduction Regulation Of Apoptotic Process Movement Of Cell Or Subcellular Component Positive Regulation Of Catalytic Activity Regulation Of Cell Death Generation Of Neurons
Tagcloud ?		atrophin beyond bind containing e3 endocytic extends interacting itch ligase ligases motifs nedd4 nexin pool possess prd proline py sh3 snx9 sorting substrates truncated ubiquitin ubiquitylates ubiquitylation ww