SNX18 and HSPB2-C11orf52

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SNX18	HSPB2-C11orf52
Description		sorting nexin 18	HSPB2-C11orf52 readthrough (NMD candidate)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Plasma Membrane Cytoplasmic Side Of Plasma Membrane Endosome Membrane Endomembrane System Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Recycling Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Lipid Binding Phosphatidylinositol Binding
	Biological Process	Mitotic Cell Cycle Mitotic Cytokinesis Endocytosis Positive Regulation Of Catabolic Process Protein Transport Endosomal Transport Cleavage Furrow Formation Positive Regulation Of GTPase Activity Cell Division Plasma Membrane Tubulation Positive Regulation Of Autophagosome Assembly
Pathways		Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Immune response to smallpox vaccine (IL-6) ( 22542470)	Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		19 interacting genes: ABI2 CPSF7 CYSRT1 DPPA4 GABARAP GOLGA2 HSF2BP HSPB2 HSPB2-C11orf52 KHDRBS3 KRTAP1-1 KRTAP6-3 MAP1LC3B MDFI MSS51 PTPN21 SOS1 SOS2 ZBTB42	20 interacting genes: A1CF BAG3 BEX2 BICRAL CEP19 ENKD1 HOXB9 KANK2 LMO1 LMO3 MISP PATZ1 POGZ PRR35 RFPL3 SNX18 TLX3 VEZF1 WWOX YPEL3
Entrez ID		112574	100528019
HPRD ID		15407
Ensembl ID		ENSG00000178996	ENSG00000254445
Uniprot IDs		Q96RF0
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Pro-B Cell Differentiation Regulation Of Lymphoid Progenitor Cell Differentiation Mitophagy Autophagy Of Mitochondrion Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding SH3 Domain Binding Regulation Of T Cell Differentiation In Thymus B Cell Homeostasis Macroautophagy Regulation Of Hematopoietic Progenitor Cell Differentiation	Regulation Of Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Ciliary Basal Body Organelle Assembly Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Establishment Of Mitotic Spindle Orientation Vesicle Targeting, Trans-Golgi To Periciliary Membrane Compartment
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