CAP1 and CAP2

Number of citations of the paper that reports this interaction (PMID 8761950)
6

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo, two hybrid)

		CAP1	CAP2
Gene Name		CAP, adenylate cyclase-associated protein 1 (yeast)	CAP, adenylate cyclase-associated protein, 2 (yeast)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Focal Adhesion Cortical Actin Cytoskeleton Extracellular Vesicular Exosome	Plasma Membrane
	Molecular Function	Actin Binding	Actin Binding
	Biological Process	Ameboidal-type Cell Migration Platelet Degranulation Receptor-mediated Endocytosis Establishment Or Maintenance Of Cell Polarity Signal Transduction Activation Of Adenylate Cyclase Activity Axon Guidance Blood Coagulation Actin Cytoskeleton Organization Platelet Activation	Cytoskeleton Organization Establishment Or Maintenance Of Cell Polarity Signal Transduction Activation Of Adenylate Cyclase Activity Axon Guidance
Pathways		Role of Abl in Robo-Slit signaling Axon guidance Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation Signaling by Robo receptor	Role of Abl in Robo-Slit signaling Axon guidance Signaling by Robo receptor
Drugs
Diseases
GWAS			Height ( 18391951)
Protein-Protein Interactions		9 interactors: ACTB ACTG1 BARD1 CAP2 LIG4 MYOC PLA2G4A SERPINB8 UCHL5	7 interactors: ACTB ACTG1 CAP1 CFL2 MT1P3 PRPF40A YWHAE
Entrez ID		10487	10486
HPRD ID		09869	10808
Ensembl ID		ENSG00000131236	ENSG00000112186
Uniprot IDs		D3DPU2 Q01518	B7Z1C4 B7Z214 B7Z385 E9PDI2 P40123 Q5JPJ8
PDB IDs		1K8F
Enriched GO Terms of Interacting Partners?		Tissue Homeostasis Platelet Activation Nervous System Development Cell Activation Multicellular Organismal Homeostasis Platelet Aggregation Generation Of Neurons Neuron Projection Development Neurogenesis Homotypic Cell-cell Adhesion Enzyme Linked Receptor Protein Signaling Pathway Retina Homeostasis Cellular Response To Stimulus Cell Development Neuron Development Axon Guidance ERBB2-ERBB3 Signaling Pathway DNA Ligation Involved In DNA Recombination Skeletal Muscle Hypertrophy Blood Coagulation Hemostasis Midbrain Development Adherens Junction Organization Neuron Differentiation Response To Stress Cell Projection Organization Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway ERBB2 Signaling Pathway Negative Regulation Of MRNA 3'-end Processing Single Organismal Cell-cell Adhesion Axonogenesis Axon Development Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation DNA Repair Wound Healing Chemotaxis Response To Stimulus Neuron Projection Morphogenesis Platelet Activating Factor Biosynthetic Process System Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Platelet Activating Factor Metabolic Process Response To Wounding Cell Morphogenesis Involved In Differentiation Regulation Of Cellular Process See more	Locomotion Movement Of Cell Or Subcellular Component Organelle Organization Generation Of Neurons Neurogenesis Platelet Activation Substantia Nigra Development Platelet Aggregation Nervous System Development Sarcomere Organization Cytoskeleton Organization Neural Nucleus Development Axon Guidance Retina Homeostasis Blood Coagulation Hemostasis Immune Response-regulating Signaling Pathway Myofibril Assembly Midbrain Development Adherens Junction Organization Axonogenesis Ephrin Receptor Signaling Pathway Axon Development Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Actin Cytoskeleton Organization Wound Healing Chemotaxis Actomyosin Structure Organization Cell Differentiation Actin Filament-based Process Positive Regulation Of Immune Response Neuron Projection Morphogenesis Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Activation Cell Development Response To Wounding Negative Regulation Of Peptidyl-serine Dephosphorylation Regulation Of Heart Rate By Hormone Cell Morphogenesis Involved In Differentiation Striated Muscle Cell Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Innate Immune Response Muscle Cell Development Neuron Projection Development Cell Migration See more
Tagcloud ?		alarco albicans balan brefeldin bzip caglr1 cai4 catrr1 caycf1 cdr1 cdr2 cerulenin cjd21 diamide facilitator fcz flr1 fr2 hyperactive hyperresistant mainville mdr1 nitroquinoline phenanthroline raymond reintroduction talibi transformants yap1	ac aided bpd cap1 computer correlations decided enzymatic fetal fl hc isooxytocinase klimek labor maturity measurements oxytocinase pictures prediction pregnancies relations remaining simultaneously sterility stronger takes ultrasonographic ultrasound verify
Tagcloud (Difference) ?		alarco albicans balan brefeldin bzip caglr1 cai4 catrr1 caycf1 cdr1 cdr2 cerulenin cjd21 diamide facilitator fcz flr1 fr2 hyperactive hyperresistant mainville mdr1 nitroquinoline phenanthroline raymond reintroduction talibi transformants yap1	ac aided bpd computer correlations decided enzymatic fetal fl hc isooxytocinase klimek labor maturity measurements oxytocinase pictures prediction pregnancies relations remaining simultaneously sterility stronger takes ultrasonographic ultrasound verify
Tagcloud (Intersection) ?		cap1