CAP1 and SERPINB8

Number of citations: 0 (PubMedID 8761950)
Data Source: HPRD (two hybrid, in vivo)

		CAP1	SERPINB8
Name		cyclase associated actin cytoskeleton regulatory protein 1	serpin family B member 8
Structure			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane Focal Adhesion Membrane Cortical Actin Cytoskeleton Azurophil Granule Lumen Extracellular Exosome Presynapse Postsynapse Glutamatergic Synapse	Extracellular Space Cytoplasm Cytosol Extracellular Matrix Extracellular Exosome
	Molecular Function	Actin Binding Protein Binding Adenylate Cyclase Binding	Serine-type Endopeptidase Inhibitor Activity Protein Binding Peptidase Inhibitor Activity
	Biological Process	Cell Morphogenesis Ameboidal-type Cell Migration Receptor-mediated Endocytosis Cytoskeleton Organization Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Signal Transduction Activation Of Adenylate Cyclase Activity CAMP-mediated Signaling Actin Cytoskeleton Organization Modification Of Postsynaptic Actin Cytoskeleton	Negative Regulation Of Endopeptidase Activity Epithelial Cell-cell Adhesion
Pathways		Platelet degranulation Role of ABL in ROBO-SLIT signaling Neutrophil degranulation	Dissolution of Fibrin Clot
GWAS		Refractive error ( 32231278 )	Airflow obstruction ( 22837378 )
Novel Interactors		1 novel interactors: SUOX	None recorded
Interacting Genes		13 interacting genes: ACTB ACTG1 BARD1 CAP2 CEBPA CFTR FNDC3B LIG4 MYOC PLA2G4A SERPINB8 SNCA UCHL5	5 interacting genes: CAP1 F10 F2 FURIN PRSS1
Entrez ID		10487	5271
HPRD ID		09869	03412
Ensembl ID		ENSG00000131236	ENSG00000166401
Uniprot IDs		D3DPU2 Q01518	A0A1B0GU38 P50452
PDB IDs		1K8F	Not available
GO Terms Enriched among Interactors		Regulation Of Norepinephrine Uptake Transporter Regulator Activity Regulation Of Synaptic Vesicle Recycling Regulation Of Transepithelial Transport Dense Body Morphogenesis Of A Polarized Epithelium Structural Constituent Of Postsynaptic Actin Cytoskeleton Regulation Of Macrophage Activation Multicellular Organismal-level Homeostasis Cellular Response To Lithium Ion Postsynaptic Actin Cytoskeleton Organization Response To Lithium Ion Protein Localization To Cell-cell Junction Calyx Of Held Postsynaptic Cytoskeleton Organization Regulation Of Synaptic Vesicle Endocytosis Regulation Of Protein Catabolic Process Regulation Of Organelle Organization NuA4 Histone Acetyltransferase Complex Apical Junction Complex Positive Regulation Of Macrophage Activation Maintenance Of Blood-brain Barrier Homeostatic Process Cellular Response To Metal Ion Anatomical Structure Homeostasis Tissue Homeostasis Kinesin Binding Platelet Aggregation Tau Protein Binding Regulation Of DNA Repair Positive Regulation Of Norepinephrine Uptake Cellular Response To Cytochalasin B Regulation Of Vesicle-mediated Transport Basal Body Patch Negative Regulation Of MRNA 3'-end Processing RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Establishment Of Integrated Proviral Latency Positive Regulation Of Organelle Organization Skeletal Muscle Hypertrophy Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Sulfite Oxidase Activity DNA Recombination Regulation Of Chromosome Organization	Serine-type Peptidase Activity Serine-type Endopeptidase Activity Golgi Lumen Peptidase Activity Extracellular Region Extracellular Matrix Disassembly Proteolysis Endopeptidase Activity Extracellular Space Negative Regulation Of Nerve Growth Factor Production Dibasic Protein Processing Zymogen Inhibition Hydrolase Activity Coagulation Blood Coagulation Hemostasis Blood Microparticle Golgi Apparatus Subcompartment Regulation Of Nerve Growth Factor Production Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Nerve Growth Factor Production Negative Regulation Of Neurotrophin Production Negative Regulation Of Proteolysis Heparin Binding Negative Regulation Of Receptor Catabolic Process Thrombospondin Receptor Activity Viral Translation Viral Life Cycle CAMP-mediated Signaling Neutrophil-mediated Killing Of Gram-negative Bacterium Cytokine Precursor Processing Nerve Growth Factor Binding Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Negative Regulation Of Transforming Growth Factor Beta1 Production Positive Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Extracellular Matrix Organization Extracellular Structure Organization Heparan Sulfate Binding Regulation Of Body Fluid Levels Signal Peptide Processing Endoplasmic Reticulum Lumen Thrombin-activated Receptor Signaling Pathway Neutrophil-mediated Killing Of Bacterium Cytolysis By Host Of Symbiont Cells Negative Regulation Of Fibrinolysis Negative Regulation Of Transforming Growth Factor Beta Production Adenylate Cyclase Binding Modification Of Postsynaptic Actin Cytoskeleton Protein Metabolic Process Negative Regulation Of Cytokine Production