PPIH and PRPF4

Number of citations of the paper that reports this interaction (PMID 12875835)
10

Data Source:
HPRD (in vitro)

		PPIH	PRPF4
Gene Name		peptidylprolyl isomerase H (cyclophilin H)	pre-mRNA processing factor 4
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Gene Ontology Annotations	Cellular Component	Spliceosomal Complex Cytoplasm Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U4/U6 SnRNP	Nucleus Nucleoplasm Spliceosomal Complex Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U4/U6 SnRNP
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Ribonucleoprotein Complex Binding	Protein Binding U6 SnRNA Binding U4 SnRNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding Protein Complex Assembly Positive Regulation Of Viral Genome Replication	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing Gene Expression
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: BAG2 N4BP2L2 NHP2L1 PRPF18 PRPF3 PRPF31 PRPF4	12 interactors: APP ATP5J2 CLK1 GPKOW NHP2L1 PPIH PRPF3 PRPF31 SRSF1 TGFBR1 U2AF1 WBP4
Entrez ID		10465	9128
HPRD ID		12084	08479
Ensembl ID		ENSG00000171960	ENSG00000136875
Uniprot IDs		O43447 Q6FH36	O43172 Q5T1M7
PDB IDs		1MZW 1QOI	1MZW
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal Tri-snRNP Complex Assembly RNA Metabolic Process Spliceosomal SnRNP Assembly Gene Expression Ribonucleoprotein Complex Biogenesis Negative Regulation Of Hematopoietic Stem Cell Differentiation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Hematopoietic Stem Cell Proliferation Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Regulation Of Hematopoietic Stem Cell Differentiation Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Cellular Metabolic Process Regulation Of Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Stem Cell Differentiation Cellular Macromolecular Complex Assembly	MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing RNA Splicing MRNA 3'-end Processing Spliceosomal Tri-snRNP Complex Assembly Ribonucleoprotein Complex Biogenesis RNA 3'-end Processing MRNA Cis Splicing, Via Spliceosome RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Ribonucleoprotein Complex Assembly Cellular Nitrogen Compound Metabolic Process Spliceosomal SnRNP Assembly Termination Of RNA Polymerase II Transcription Nitrogen Compound Metabolic Process Peptidyl-threonine Phosphorylation MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus Cellular Metabolic Process Synaptic Growth At Neuromuscular Junction Regulation Of RNA Splicing Collateral Sprouting In Absence Of Injury Cellular Component Assembly Peptidyl-serine Phosphorylation Nuclear Export MRNA Transport RNA Transport Regulation Of Protein Binding Collateral Sprouting Axon Midline Choice Point Recognition MRNA 5'-splice Site Recognition RNA Localization Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Cellular Macromolecular Complex Assembly Parathyroid Gland Development Neuron Remodeling Intracellular Transport Endothelial Cell Activation
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