PPIH and NHP2L1

Number of citations of the paper that reports this interaction (PMID 16723661)
44

Data Source:
BioGRID (two hybrid)

		PPIH	NHP2L1
Gene Name		peptidylprolyl isomerase H (cyclophilin H)	NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
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Gene Ontology Annotations	Cellular Component	Spliceosomal Complex Cytoplasm Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U4/U6 SnRNP	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Box C/D SnoRNP Complex Protein Complex
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Ribonucleoprotein Complex Binding	RNA Binding Protein Binding SnoRNA Binding Poly(A) RNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding Protein Complex Assembly Positive Regulation Of Viral Genome Replication	MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression Ribosome Biogenesis
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: BAG2 N4BP2L2 NHP2L1 PRPF18 PRPF3 PRPF31 PRPF4	14 interactors: CDKN2C CHST1 GTF3C1 LRIF1 MAP1LC3B POLA2 PPIH PRPF3 PRPF31 PRPF4 RAD17 RBM10 SNW1 XRCC6
Entrez ID		10465	4809
HPRD ID		12084	03197
Ensembl ID		ENSG00000171960	ENSG00000100138
Uniprot IDs		O43447 Q6FH36	P55769 Q6FHM6
PDB IDs		1MZW 1QOI	1E7K 2JNB 2OZB 3SIU 3SIV
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal Tri-snRNP Complex Assembly RNA Metabolic Process Spliceosomal SnRNP Assembly Gene Expression Ribonucleoprotein Complex Biogenesis Negative Regulation Of Hematopoietic Stem Cell Differentiation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Hematopoietic Stem Cell Proliferation Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Regulation Of Hematopoietic Stem Cell Differentiation Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Cellular Metabolic Process Regulation Of Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Stem Cell Differentiation Cellular Macromolecular Complex Assembly	RNA Splicing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Spliceosomal Tri-snRNP Complex Assembly RNA Metabolic Process Gene Expression Cellular Metabolic Process Spliceosomal SnRNP Assembly Positive Regulation Of Viral Process Telomere Maintenance Positive Regulation Of Vitamin D Receptor Signaling Pathway Cellular Hyperosmotic Salinity Response Macromolecule Biosynthetic Process 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter Cellular Response To X-ray Regulation Of Vitamin D Receptor Signaling Pathway Regulation Of Viral Process G1/S Transition Of Mitotic Cell Cycle TRNA Transcription Ribonucleoprotein Complex Assembly Establishment Of Integrated Proviral Latency Metabolic Process Cellular Hyperosmotic Response Hyperosmotic Salinity Response Establishment Of Viral Latency Positive Regulation By Host Of Viral Transcription Mitotic Cell Cycle Process DNA Replication Checkpoint Cellular Response To Salt Stress DNA Recombination Mitotic Cell Cycle DNA Ligation
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