PPIH and N4BP2L2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PPIH	N4BP2L2
Gene Name		peptidylprolyl isomerase H (cyclophilin H)	NEDD4 binding protein 2-like 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Spliceosomal Complex Cytoplasm Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U4/U6 SnRNP	Transcriptional Repressor Complex Extracellular Vesicular Exosome
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Cyclosporin A Binding Ribonucleoprotein Complex Binding	RNA Polymerase II Transcription Corepressor Activity Molecular_function Protein Binding Enzyme Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Peptidyl-prolyl Isomerization Protein Folding Protein Complex Assembly Positive Regulation Of Viral Genome Replication	Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Hematopoietic Stem Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Breast cancer ( 23535729)
Protein-Protein Interactions		7 interactors: BAG2 N4BP2L2 NHP2L1 PRPF18 PRPF3 PRPF31 PRPF4	4 interactors: HOXA1 LMO2 NAA38 PPIH
Entrez ID		10465	10443
HPRD ID		12084	15119
Ensembl ID		ENSG00000171960	ENSG00000244754
Uniprot IDs		O43447 Q6FH36	B4DPY1 Q92802 Q9Y3H6
PDB IDs		1MZW 1QOI
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal Tri-snRNP Complex Assembly RNA Metabolic Process Spliceosomal SnRNP Assembly Gene Expression Ribonucleoprotein Complex Biogenesis Negative Regulation Of Hematopoietic Stem Cell Differentiation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Hematopoietic Stem Cell Proliferation Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Regulation Of Hematopoietic Stem Cell Differentiation Regulation Of Hematopoietic Stem Cell Proliferation Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Cellular Metabolic Process Regulation Of Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Stem Cell Differentiation Cellular Macromolecular Complex Assembly	Optokinetic Behavior Abducens Nerve Formation Facial Nucleus Development Semicircular Canal Formation Rhombomere 4 Development Rhombomere 3 Development Rhombomere 5 Development Embryonic Neurocranium Morphogenesis Negative Regulation Of Erythrocyte Differentiation Outer Ear Morphogenesis Cellular Response To Thyroid Hormone Stimulus Semicircular Canal Morphogenesis Rhombomere Development Facial Nerve Structural Organization Pons Development MRNA Transcription From RNA Polymerase II Promoter Facial Nerve Morphogenesis Semicircular Canal Development Embryonic Organ Development MRNA Transcription Response To Thyroid Hormone Parasympathetic Nervous System Development Anatomical Structure Arrangement Positive Regulation Of Viral Genome Replication Cochlea Morphogenesis Embryonic Hemopoiesis Motor Neuron Axon Guidance Regulation Of Erythrocyte Differentiation Autonomic Nervous System Development Cochlea Development RNA Metabolic Process Neural Nucleus Development Cranial Nerve Development Artery Morphogenesis
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