ZER1 and GIMAP5

Number of citations of the paper that reports this interaction (PubMedID 34214466)
0

Data Source:
BioGRID (unspecified method)

		ZER1	GIMAP5
Description		zyg-11 related cell cycle regulator	GTPase, IMAP family member 5
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GO Annotations	Cellular Component	Cul2-RING Ubiquitin Ligase Complex	Lysosome Lysosomal Membrane Endosome Endosome Membrane Membrane Multivesicular Body Membrane
	Molecular Function	Protein Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS		Axial length ( 24144296) Body mass index ( 26426971) Eating disorders (purging via substances) ( 23568457) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Interacting Genes		4 interacting genes: CUL2 GIMAP5 MLH1 ZNF701	68 interacting genes: ADGRG3 APP AQP3 AQP6 ARL13B BTNL9 CD33 CD53 CLDN7 CREB3L1 CYB561 CYBRD1 DKK4 EBP EDA EDA2R ELOVL4 EMP1 ERGIC3 EVI2B FAM174A FAM209A FAM210B FATE1 FCER1G GJA8 GJB3 GORAB GPR42 GRAMD2B IFNGR2 JAGN1 KASH5 KIR3DL3 LAYN LDLRAD1 LSMEM2 M6PR MGST2 MGST3 MILR1 MS4A14 PDZK1IP1 PTGES RETREG3 RNASEK RNF19B SCN3B SHISAL1 SLC10A1 SLC10A6 SLC35H1 SMIM3 SPACA1 STOM STX1A STX2 STX4 SYT1 TM4SF18 TM4SF19 TMEM31 TMX1 TMX2 TNFRSF19 TSPAN18 ZER1 ZFYVE27
Entrez ID		10444	55340
HPRD ID		10802	16280
Ensembl ID		ENSG00000160445	ENSG00000196329
Uniprot IDs		Q7Z7L7	A0A090N8P9 Q96F15
PDB IDs		7EP3 7EP4 7EP5 7XYS 7XYT 7XYU	6Z3E
Enriched GO Terms of Interacting Partners?		Nuclear Lumen Positive Regulation Of Protein Glycosylation Regulation Of Protein Glycosylation Golgi Disassembly Microtubule-based Process Positive Regulation Of Isotype Switching To IgA Isotypes Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Guanine/thymine Mispair Binding MutSalpha Complex Binding Male Meiosis Chromosome Segregation Homologous Chromosome Segregation MutLalpha Complex Female Meiosis Chromosome Segregation Regulation Of Mitotic Recombination Chiasma Intrinsic Apoptotic Signaling Pathway Late Recombination Nodule Mismatch Repair Complex Meiotic Metaphase I Homologous Chromosome Alignment Negative Regulation Of Mitotic Recombination Clathrin-coated Vesicle Cargo Loading, AP-3-mediated Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Establishment Of Protein Localization To Mitochondrial Membrane Involved In Mitochondrial Fission Positive Regulation Of NK T Cell Differentiation Regulation Of NK T Cell Differentiation Meiotic Telomere Clustering Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Ubiquitin Ligase Complex Scaffold Activity Importin-alpha Family Protein Binding Telomere Localization Microvesicle Golgi Cis Cisterna Golgi Ribbon Formation Mismatched DNA Binding Positive Regulation Of Isotype Switching To IgG Isotypes Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway AP-3 Adaptor Complex Spindle Midzone Assembly Clathrin Adaptor Complex Asymmetric Cell Division Somatic Hypermutation Of Immunoglobulin Genes	Membrane Protein Binding Exocytosis Plasma Membrane Endoplasmic Reticulum Membrane Secretion By Cell Identical Protein Binding Ascorbate Homeostasis Secretion Positive Regulation Of Regulated Secretory Pathway Regulated Exocytosis Glutathione Peroxidase Activity Transmembrane Monodehydroascorbate Reductase Activity Endomembrane System Vesicle Docking Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site SNARE Binding Tertiary Granule Membrane Leukotriene-C4 Synthase Activity Bile Acid:sodium Symporter Activity Vesicle-mediated Transport Glutathione Transferase Activity Cornified Envelope Assembly Endoplasmic Reticulum Organelle Localization By Membrane Tethering Calcium-ion Regulated Exocytosis Specific Granule Membrane Positive Regulation Of Exocytosis Renal Water Transport Chromaffin Granule Membrane Membrane Docking SNAP Receptor Activity Disulfide Oxidoreductase Activity Vesicle Fusion Glutathione Binding Icosanoid Biosynthetic Process Tumor Necrosis Factor Receptor Activity Nuclear Envelope Lumen SNARE Complex Organelle Membrane Fusion Positive Regulation Of Catecholamine Secretion SNARE Complex Assembly
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