ZER1

Description		zyg-11 related cell cycle regulator
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GO Annotations	Cellular Component	Cul2-RING Ubiquitin Ligase Complex
	Molecular Function	Protein Binding
	Biological Process	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS		Axial length ( 24144296) Body mass index ( 26426971) Eating disorders (purging via substances) ( 23568457) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
Novel Interacting Genes		2 novel interacting genes: AP3B1 GOLGA2
Interacting Genes		4 interacting genes: CUL2 GIMAP5 MLH1 ZNF701
Entrez ID		10444
HPRD ID		10802
Ensembl ID		ENSG00000160445
Uniprot IDs		Q7Z7L7
PDB IDs		7EP3 7EP4 7EP5 7XYS 7XYT 7XYU
Enriched GO Terms of Interacting Partners?		Nuclear Lumen Positive Regulation Of Protein Glycosylation Regulation Of Protein Glycosylation Golgi Disassembly Microtubule-based Process Positive Regulation Of Isotype Switching To IgA Isotypes Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Guanine/thymine Mispair Binding MutSalpha Complex Binding Male Meiosis Chromosome Segregation Homologous Chromosome Segregation MutLalpha Complex Female Meiosis Chromosome Segregation Regulation Of Mitotic Recombination Chiasma Intrinsic Apoptotic Signaling Pathway Late Recombination Nodule Mismatch Repair Complex Meiotic Metaphase I Homologous Chromosome Alignment Negative Regulation Of Mitotic Recombination Clathrin-coated Vesicle Cargo Loading, AP-3-mediated Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Establishment Of Protein Localization To Mitochondrial Membrane Involved In Mitochondrial Fission Positive Regulation Of NK T Cell Differentiation Regulation Of NK T Cell Differentiation Meiotic Telomere Clustering Chromosome Localization To Nuclear Envelope Involved In Homologous Chromosome Segregation Ubiquitin Ligase Complex Scaffold Activity Importin-alpha Family Protein Binding Telomere Localization Microvesicle Golgi Cis Cisterna Golgi Ribbon Formation Mismatched DNA Binding Positive Regulation Of Isotype Switching To IgG Isotypes Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway AP-3 Adaptor Complex Spindle Midzone Assembly Clathrin Adaptor Complex Asymmetric Cell Division Somatic Hypermutation Of Immunoglobulin Genes
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