CDIPT and CYB561

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CDIPT	CYB561
Description		CDP-diacylglycerol--inositol 3-phosphatidyltransferase	cytochrome b561
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane	Lysosomal Membrane Membrane Cytoplasmic Vesicle Chromaffin Granule Membrane
	Molecular Function	CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Protein Binding Transferase Activity Phosphotransferase Activity, For Other Substituted Phosphate Groups Diacylglycerol Binding Manganese Ion Binding Carbohydrate Binding Alcohol Binding Metal Ion Binding	Protein Binding Oxidoreductase Activity Metal Ion Binding Transmembrane Monodehydroascorbate Reductase Activity
	Biological Process	Lipid Metabolic Process Phosphatidylinositol Biosynthetic Process Phospholipid Biosynthetic Process CDP-diacylglycerol Metabolic Process	Intracellular Iron Ion Homeostasis Electron Transport Chain Ascorbate Homeostasis
Pathways		Synthesis of PI
Drugs		scyllo-inositol
Diseases
GWAS		Mean platelet volume ( 27863252)	Cerebrospinal fluid levels of Alzheimer's disease-related proteins ( 25340798) Diastolic blood pressure ( 28739976)
Interacting Genes		60 interacting genes: APP AQP2 AQP6 ARL13B ATP6V0E1 BSND CD79A CGRRF1 CISD2 CPLX4 CYB561 CYB5R3 DARS2 EBP ELOVL4 ERGIC3 EVI2B FAM209A FCER1G FCGR2A FFAR2 FKBP7 GJB1 GOLM1 GPR101 GPR151 GPR152 GPX8 HSD17B13 IER3IP1 IGFBP6 JAGN1 KCNK1 KIR2DL3 LNX1 MFF MGST3 MS4A14 MTIF3 ODF4 PLP1 PSCA RELL2 RETREG3 RNF19B RPLP1 RTN3 SCAI SCN3B SDCBP SIGLEC12 SLC10A1 SLC10A6 SLC16A7 SLC7A1 SSMEM1 TLCD4 TMX2 UNC93A VMA21	60 interacting genes: ANKRD46 AQP6 BEST2 BET1 BIK BNIP1 CD79A CDIPT CLDN9 CMTM2 CREB3 DARS2 EBP EDA EFNA5 EHHADH ERG28 ERGIC3 FAM209A FKBP8 GGT7 GIMAP5 GOSR2 GPR152 GPX8 HMOX1 LHFPL5 LMNA LPAR3 OPRM1 ORMDL2 PLP2 REEP6 RNF5 SCD SEC22A SERP2 SLC19A3 SLC35H1 SLC38A7 SLC39A1 SLC39A2 SMIM1 SSMEM1 STX3 SYNJ2BP TM4SF18 TMEM11 TMEM128 TMEM14B TMEM179B TMEM242 TMEM65 TMPPE TREX1 TSNARE1 UBE2J1 VAPA VAPB ZDHHC7
Entrez ID		10423	1534
HPRD ID		12063	02485
Ensembl ID		ENSG00000103502	ENSG00000008283
Uniprot IDs		A8K3L7 O14735	B3KTA1 J3QRH5 P49447
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Protein Binding Endoplasmic Reticulum Organization Plasma Membrane Identical Protein Binding Bile Acid:sodium Symporter Activity	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNAP Receptor Activity SNARE Complex Membrane Fusion Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Binding Organelle Membrane Fusion FFAT Motif Binding Mitochondrial Membrane Golgi Vesicle Transport Endoplasmic Reticulum Organization Membrane Organization Organelle Fusion COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Organelle Localization By Membrane Tethering Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum Localization Membrane Docking Vesicle Fusion Lipid Biosynthetic Process Host-mediated Activation Of Viral Genome Replication Positive Regulation Of Collateral Sprouting Host-mediated Perturbation Of Viral Genome Replication Progesterone Receptor Signaling Pathway Vesicle Organization
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