CDIPT and KIR2DL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CDIPT	KIR2DL3
Description		CDP-diacylglycerol--inositol 3-phosphatidyltransferase	killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 3
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane	Plasma Membrane Membrane
	Molecular Function	CDP-diacylglycerol-inositol 3-phosphatidyltransferase Activity Protein Binding Transferase Activity Phosphotransferase Activity, For Other Substituted Phosphate Groups Diacylglycerol Binding Manganese Ion Binding Carbohydrate Binding Alcohol Binding Metal Ion Binding	Antigen Binding Protein Binding Signaling Receptor Activity Identical Protein Binding
	Biological Process	Lipid Metabolic Process Phosphatidylinositol Biosynthetic Process Phospholipid Biosynthetic Process CDP-diacylglycerol Metabolic Process	Immune Response-regulating Signaling Pathway Immune Response
Pathways		Synthesis of PI	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs		scyllo-inositol
Diseases
GWAS		Mean platelet volume ( 27863252)
Interacting Genes		60 interacting genes: APP AQP2 AQP6 ARL13B ATP6V0E1 BSND CD79A CGRRF1 CISD2 CPLX4 CYB561 CYB5R3 DARS2 EBP ELOVL4 ERGIC3 EVI2B FAM209A FCER1G FCGR2A FFAR2 FKBP7 GJB1 GOLM1 GPR101 GPR151 GPR152 GPX8 HSD17B13 IER3IP1 IGFBP6 JAGN1 KCNK1 KIR2DL3 LNX1 MFF MGST3 MS4A14 MTIF3 ODF4 PLP1 PSCA RELL2 RETREG3 RNF19B RPLP1 RTN3 SCAI SCN3B SDCBP SIGLEC12 SLC10A1 SLC10A6 SLC16A7 SLC7A1 SSMEM1 TLCD4 TMX2 UNC93A VMA21	64 interacting genes: ADGRE2 AGTRAP AIG1 ANKRD46 APOA2 APOD APP AQP10 ASGR1 ATP6V0E1 BMP10 BRICD5 BTN2A2 C3orf52 CDIPT CISD2 CLDN19 CLN6 COQ9 CXCL16 CXCL9 CYB5B CYBC1 EMD FAM209A FAM3C FUNDC2 GAST GJA8 GPR108 GPX8 HLA-C IFITM3 INSIG2 ITGAM JAGN1 KTN1 LAT LCK LEUTX LHFPL5 NINJ2 NRM NSG1 OLFM4 PLN PLPPR2 PTPN6 RNF152 RTP2 SEC22B SLC38A7 SMIM1 SNORC THBD TMEM218 TMEM222 TMEM243 TMEM86B TMEM97 TRAF3IP3 UPK1B UPK2 VAMP5
Entrez ID		10423	3804
HPRD ID		12063	10383
Ensembl ID		ENSG00000103502	ENSG00000243772
Uniprot IDs		A8K3L7 O14735	E3NZD8 P43628
PDB IDs			1B6U 6PAG 8TUI
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Protein Binding Endoplasmic Reticulum Organization Plasma Membrane Identical Protein Binding Bile Acid:sodium Symporter Activity	Membrane Protein Binding Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cholesterol Binding CD27 Signaling Pathway
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