BASP1 and GAD1

Number of citations of the paper that reports this interaction (PubMedID 23376695)
0

Data Source:
BioGRID (pull down, pull down)

		BASP1	GAD1
Description		brain abundant membrane attached signal protein 1	glutamate decarboxylase 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm Cytoskeleton Plasma Membrane COP9 Signalosome Membrane Nuclear Matrix PML Body Nuclear Speck Cell Junction Growth Cone Vesicle Cell Projection Extracellular Exosome	Cytoplasm Plasma Membrane Cell Cortex Vesicle Membrane Axon Axon Terminus Neuron Projection Terminus Synapse Perinuclear Region Of Cytoplasm Presynaptic Active Zone Inhibitory Synapse Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Presynapse GABA-ergic Synapse
	Molecular Function	Transcription Cis-regulatory Region Binding Transcription Corepressor Activity Protein Binding Calmodulin Binding Protein Domain Specific Binding	Glutamate Decarboxylase Activity Protein Binding Lyase Activity Carbon-carbon Lyase Activity Carboxy-lyase Activity Pyridoxal Phosphate Binding Identical Protein Binding
	Biological Process	Thorax And Anterior Abdomen Determination Gonad Development Substantia Nigra Development Negative Regulation Of DNA-templated Transcription Protein Homooligomerization Mesenchymal To Epithelial Transition Positive Regulation Of Heart Growth Diaphragm Development Metanephric Mesenchyme Development Podocyte Differentiation Supramolecular Fiber Organization Positive Regulation Of Metanephric Ureteric Bud Development	L-glutamate Catabolic Process Gamma-aminobutyrate Shunt Chemical Synaptic Transmission Gamma-aminobutyric Acid Biosynthetic Process Carboxylic Acid Metabolic Process Social Behavior Locomotory Exploration Behavior
Pathways		RHOF GTPase cycle	GABA synthesis GABA synthesis, release, reuptake and degradation MECP2 regulates transcription of genes involved in GABA signaling
Drugs			Pyridoxal phosphate Pyridoxal phosphate Glutamic acid
Diseases			Cerebral palsy
GWAS		Bipolar disorder with mood-incongruent psychosis ( 23092984) Melanoma ( 28212542) Obesity in adult survivors of childhood cancer exposed to cranial radiation ( 25963547) Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681)	Menopause (age at onset) ( 26414677)
Interacting Genes		7 interacting genes: AGTR1 ATXN1 GAD1 GAD2 SERPINB5 SNCA TRIM37	18 interacting genes: AGTRAP BASP1 CALM1 CMTM5 GAD2 HAAO KRT31 KRT40 KRTAP3-2 MAL2 PPP2CA PPP2CB PRKACA PRKCE SNCA STK3 TRIM23 TRIP6
Entrez ID		10409	2571
HPRD ID		08389	12011
Ensembl ID		ENSG00000176788	ENSG00000128683
Uniprot IDs		P80723	A0A0S2Z3V5 Q8IVA8 Q99259
PDB IDs			2OKJ 3VP6
Enriched GO Terms of Interacting Partners?		Gamma-aminobutyrate Shunt Glutamate Decarboxylase Activity Gamma-aminobutyric Acid Biosynthetic Process L-glutamate Catabolic Process Gamma-aminobutyric Acid Metabolic Process Succinate Metabolic Process Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Carbon-carbon Lyase Activity Dicarboxylic Acid Catabolic Process Carboxy-lyase Activity Locomotory Behavior Glutamate Metabolic Process Trans-synaptic Signaling Social Behavior Pyridoxal Phosphate Binding Glutamine Family Amino Acid Metabolic Process Chemical Synaptic Transmission Axon Terminus Synaptic Signaling Excitatory Postsynaptic Potential Amino Acid Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process Angiotensin Type I Receptor Activity Axon Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Proteinogenic Amino Acid Catabolic Process L-amino Acid Catabolic Process Adult Locomotory Behavior Dicarboxylic Acid Metabolic Process Monocarboxylic Acid Metabolic Process Regulation Of Postsynaptic Membrane Potential Bradykinin Receptor Binding Amino Acid Catabolic Process Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Phospholipase C-activating Angiotensin-activated Signaling Pathway Renin-angiotensin Regulation Of Aldosterone Production Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Regulation Of Reactive Oxygen Species Metabolic Process Cell-cell Signaling Angiotensin Type II Receptor Activity Signaling Negative Regulation Of Cytoskeleton Organization	Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Cytoskeleton Negative Regulation Of Glycolytic Process Through Fructose-6-phosphate Regulation Of Sequestering Of Calcium Ion Tau Protein Binding Regulation Of Calcium Ion Transmembrane Transport Response To Metal Ion Dopamine Biosynthetic Process Regulation Of Microtubule Polymerization Enzyme Activator Activity Cellular Response To Epinephrine Stimulus Regulation Of Calcium Ion Transport Vascular Endothelial Cell Response To Fluid Shear Stress Response To Epinephrine Synaptic Transmission, Dopaminergic Regulation Of Monoatomic Cation Transmembrane Transport Cytosol Keratin Filament Regulation Of Microtubule Polymerization Or Depolymerization FAR/SIN/STRIPAK Complex Negative Regulation Of Glycolytic Process Protein Phosphatase Type 2A Complex Response To Lead Ion Catecholamine Biosynthetic Process Regulation Of Monoatomic Ion Transmembrane Transport Ferrous Iron Binding Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Chemical Synaptic Transmission Negative Regulation Of ATP Metabolic Process Calcium Channel Complex Phosphate-containing Compound Metabolic Process Regulation Of Generation Of Precursor Metabolites And Energy Trans-synaptic Signaling Regulation Of Metal Ion Transport Synaptic Signaling Dopamine Metabolic Process Positive Regulation Of Synaptic Transmission Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Cellular Response To Fluid Shear Stress Cell Communication Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Spindle Pole L-amino Acid Metabolic Process Intermediate Filament Biogenic Amine Biosynthetic Process Amine Biosynthetic Process Regulation Of Microtubule Cytoskeleton Organization Regulation Of Supramolecular Fiber Organization Aromatic Amino Acid Metabolic Process Presynaptic Endocytosis
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