BASP1 and GAD2

Number of citations of the paper that reports this interaction (PubMedID 23376695)
0

Data Source:
BioGRID (pull down, pull down)

		BASP1	GAD2
Description		brain abundant membrane attached signal protein 1	glutamate decarboxylase 2
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm Cytoskeleton Plasma Membrane COP9 Signalosome Membrane Nuclear Matrix PML Body Nuclear Speck Cell Junction Growth Cone Vesicle Cell Projection Extracellular Exosome	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Axon Cytoplasmic Vesicle Presynaptic Membrane Cell Projection Synapse Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
	Molecular Function	Transcription Cis-regulatory Region Binding Transcription Corepressor Activity Protein Binding Calmodulin Binding Protein Domain Specific Binding	Glutamate Decarboxylase Activity Protein Binding Lyase Activity Carbon-carbon Lyase Activity Carboxy-lyase Activity Pyridoxal Phosphate Binding
	Biological Process	Thorax And Anterior Abdomen Determination Gonad Development Substantia Nigra Development Negative Regulation Of DNA-templated Transcription Protein Homooligomerization Mesenchymal To Epithelial Transition Positive Regulation Of Heart Growth Diaphragm Development Metanephric Mesenchyme Development Podocyte Differentiation Supramolecular Fiber Organization Positive Regulation Of Metanephric Ureteric Bud Development	Gamma-aminobutyrate Shunt Chemical Synaptic Transmission Gamma-aminobutyric Acid Biosynthetic Process Carboxylic Acid Metabolic Process
Pathways		RHOF GTPase cycle	GABA synthesis GABA synthesis, release, reuptake and degradation MECP2 regulates transcription of genes involved in GABA signaling
Drugs			Pyridoxal phosphate Glutamic acid
Diseases
GWAS		Bipolar disorder with mood-incongruent psychosis ( 23092984) Melanoma ( 28212542) Obesity in adult survivors of childhood cancer exposed to cranial radiation ( 25963547) Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681)	Fasting glucose ( 34059833) Glycated hemoglobin levels ( 34059833) Lean body mass ( 28552196)
Interacting Genes		7 interacting genes: AGTR1 ATXN1 GAD1 GAD2 SERPINB5 SNCA TRIM37	48 interacting genes: ABHD5 AGTRAP APOC2 APOC4 ARL13B ARL6IP1 ARMC12 BASP1 BSND CACNG1 CALM1 CMTM5 CPLX4 CYB561D1 DERL1 DERL3 DGAT2L6 DMKN F10 FADS6 FAM114A2 FAM163A FTCD GAD1 HIGD1C LDAF1 LIME1 MAL2 MEST MRM3 PBX3 PLIN3 PRKACA PRKCE RDH10 RHEX RPRM SCAMP1 SDR16C5 SEC22A SMPD2 SPG21 SYCE2 SYNGR3 TMEM120B TMEM128 TNFRSF10D TSPAN33
Entrez ID		10409	2572
HPRD ID		08389	11817
Ensembl ID		ENSG00000176788	ENSG00000136750
Uniprot IDs		P80723	Q05329 Q5VZ30
PDB IDs			1ES0 2OKK 7LZ6
Enriched GO Terms of Interacting Partners?		Gamma-aminobutyrate Shunt Glutamate Decarboxylase Activity Gamma-aminobutyric Acid Biosynthetic Process L-glutamate Catabolic Process Gamma-aminobutyric Acid Metabolic Process Succinate Metabolic Process Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Carbon-carbon Lyase Activity Dicarboxylic Acid Catabolic Process Carboxy-lyase Activity Locomotory Behavior Glutamate Metabolic Process Trans-synaptic Signaling Social Behavior Pyridoxal Phosphate Binding Glutamine Family Amino Acid Metabolic Process Chemical Synaptic Transmission Axon Terminus Synaptic Signaling Excitatory Postsynaptic Potential Amino Acid Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Metabolic Process Angiotensin Type I Receptor Activity Axon Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Proteinogenic Amino Acid Catabolic Process L-amino Acid Catabolic Process Adult Locomotory Behavior Dicarboxylic Acid Metabolic Process Monocarboxylic Acid Metabolic Process Regulation Of Postsynaptic Membrane Potential Bradykinin Receptor Binding Amino Acid Catabolic Process Regulation Of Norepinephrine Uptake Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Positive Regulation Of Hydrogen Peroxide Catabolic Process Phospholipase C-activating Angiotensin-activated Signaling Pathway Renin-angiotensin Regulation Of Aldosterone Production Negative Regulation Of Serotonin Uptake Transporter Regulator Activity Negative Regulation Of Chaperone-mediated Autophagy Regulation Of Reactive Oxygen Species Metabolic Process Cell-cell Signaling Angiotensin Type II Receptor Activity Signaling Negative Regulation Of Cytoskeleton Organization	Membrane Lipid Droplet Positive Regulation Of Lipid Metabolic Process Positive Regulation Of Lipid Catabolic Process Regulation Of Calcium Ion Transmembrane Transport Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Protein Binding Positive Regulation Of Triglyceride Catabolic Process Signal Recognition Particle Binding Substantia Nigra Development Endoplasmic Reticulum Regulation Of Lipid Storage Regulation Of Calcium Ion Transport
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