MAGOHB and RBM8A

Number of citations of the paper that reports this interaction (PubMedID 16501559)
0

Data Source:
HPRD (in vivo)

		MAGOHB	RBM8A
Description		mago homolog B, exon junction complex subunit	RNA binding motif protein 8A
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Exon-exon Junction Complex Neuronal Cell Body U2-type Precatalytic Spliceosome U2-type Catalytic Step 1 Spliceosome Catalytic Step 2 Spliceosome Exon-exon Junction Subcomplex Mago-y14	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol Nuclear Speck Dendrite Exon-exon Junction Complex Neuronal Cell Body U2-type Catalytic Step 1 Spliceosome Catalytic Step 2 Spliceosome Exon-exon Junction Subcomplex Mago-y14
	Molecular Function	RNA Binding Protein Binding	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Splicing, Via Spliceosome MRNA Processing MRNA Export From Nucleus RNA Splicing Regulation Of MRNA Processing MRNA Transport Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Processing MRNA Processing MRNA Export From Nucleus Regulation Of Translation RNA Splicing Regulation Of MRNA Processing MRNA Transport Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Interacting Genes		74 interacting genes: ADAMTSL4 AMOTL2 BEND7 C18orf54 CALCOCO2 CARD10 CCDC102B CCDC106 CCDC33 CEBPA DVL2 DVL3 EFHC2 FHL5 FXR1 GNPDA2 GOLGA2 GPANK1 HMG20A HSF2BP IHO1 IKZF1 IKZF3 INCA1 KRT40 KRT75 KRTAP1-1 KRTAP13-2 MID2 NDUFB7 PARD6B PAX7 PBX4 PKP2 PRPH PRPSAP1 PTPN21 RBAK RBM8A RBMX REL RUNDC3A SNW1 SPATA6 SPDYE4 STX11 TADA2A TCF4 TERF2 TERF2IP THAP7 TLE5 TRA2A TRA2B TRIM27 TRIM42 YWHAG ZBTB10 ZBTB42 ZFP14 ZFYVE1 ZNF19 ZNF250 ZNF398 ZNF426 ZNF438 ZNF446 ZNF449 ZNF547 ZNF566 ZNF57 ZNF620 ZNF774 ZNF835	17 interacting genes: APP CDC42 DPH1 EIF4A3 FBXO25 IKBKG IPO13 KAT2B MAGOH MAGOHB MCM7 SF3B2 SRPK2 TCF12 TOE1 UPF3A UPF3B
Entrez ID		55110	9939
HPRD ID		08544	05609
Ensembl ID		ENSG00000111196	ENSG00000265241
Uniprot IDs		F5H6P7 Q96A72	A0A023T787 Q9Y5S9
PDB IDs		5XJC 5YZG 6ICZ 6QDV	1P27 2HYI 2J0Q 2J0S 2XB2 3EX7 5XJC 5YZG 6ICZ 6QDV 7A5P 7W59 7W5A 7W5B 7ZNJ 8C6J 8I0W 9FMD
Enriched GO Terms of Interacting Partners?		Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of Primary Metabolic Process Zinc Ion Binding Regulation Of Macromolecule Biosynthetic Process Protein Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of MRNA Splicing, Via Spliceosome Nucleus Negative Regulation Of DNA Recombination At Telomere Positive Regulation Of RNA Splicing Identical Protein Binding Intermediate Filament Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Nucleobase-containing Compound Metabolic Process Telomeric DNA Binding Intermediate Filament Organization Regulation Of MRNA Processing Shelterin Complex Protection From Non-homologous End Joining At Telomere Positive Regulation Of MRNA Metabolic Process Protein Domain Specific Binding Positive Regulation Of Neuron Projection Arborization Positive Regulation Of RNA Metabolic Process Nuclear Telomere Cap Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Keratin Filament G-rich Strand Telomeric DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Protein Localization To Chromosome, Telomeric Region Spliceosomal Complex Regulation Of RNA Splicing Telomere Capping Metal Ion Binding Telomere Maintenance In Response To DNA Damage	Exon-exon Junction Complex Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear-transcribed MRNA Catabolic Process MRNA Transport MRNA Catabolic Process Regulation Of MRNA Processing RNA Transport Nucleus Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing RNA Catabolic Process MRNA Metabolic Process Nucleobase-containing Compound Transport Catalytic Step 2 Spliceosome Exon-exon Junction Subcomplex Mago-y14 Nuclear Speck Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Cis Splicing, Via Spliceosome Nucleoplasm Positive Regulation Of Gene Expression Macromolecule Metabolic Process Nucleobase-containing Compound Catabolic Process RNA Splicing Nucleolus Spliceosomal Complex RNA Metabolic Process MRNA Export From Nucleus MRNA Splicing, Via Spliceosome Regulation Of Translation RNA Splicing, Via Transesterification Reactions MRNA Processing U2-type Catalytic Step 1 Spliceosome Nucleic Acid Metabolic Process RNA Export From Nucleus Negative Regulation Of Gene Expression Positive Regulation Of Neuron Differentiation Nuclear Transport Nucleocytoplasmic Transport RNA Processing Positive Regulation Of Glycolytic Process Regulation Of Attachment Of Spindle Microtubules To Kinetochore Cytoplasm Post-transcriptional Regulation Of Gene Expression Nuclear Export Positive Regulation Of Cell Cycle Regulation Of Nucleobase-containing Compound Metabolic Process Mitotic Spindle Positive Regulation Of MRNA Splicing, Via Spliceosome Neuronal Cell Body
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