TOB1 and CORO7

Number of citations of the paper that reports this interaction (PMID 21130766)
0

Data Source:
BioGRID (enzymatic study)

		TOB1	CORO7
Gene Name		transducer of ERBB2, 1	coronin 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm CCR4-NOT Complex	Golgi Membrane Golgi Apparatus Trans-Golgi Network Cytosol Actin Cytoskeleton Membrane Integral Component Of Membrane Cytoplasmic Membrane-bounded Vesicle
	Molecular Function	Transcription Corepressor Activity SH3/SH2 Adaptor Activity Protein Binding Receptor Tyrosine Kinase Binding SMAD Binding	Actin Binding Protein Binding Actin Filament Binding
	Biological Process	SMAD Protein Import Into Nucleus Negative Regulation Of Cell Proliferation Positive Regulation Of Signal Transduction Negative Regulation Of Translation Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Negative Regulation Of Nucleic Acid-templated Transcription	Golgi To Endosome Transport Protein Transport Actin Cytoskeleton Organization Actin Filament Polymerization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: APP CDC7 CNOT7 CORO7 DTL ERBB2 MAPK1 MAPK9 MARCKS PABPC1 SCMH1 SETDB1 SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD6 SMAD9	8 interactors: ACTB AP1M1 AP2M1 EPS15 KLHL20 SRC TOB1 ZRANB1
Entrez ID		10140	79585
HPRD ID		09273	07975
Ensembl ID		ENSG00000141232	ENSG00000262246
Uniprot IDs		P50616	B3KSY4 P57737
PDB IDs		2D5R 2Z15
Enriched GO Terms of Interacting Partners?		Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development Cellular Response To Growth Factor Stimulus Positive Regulation Of Macromolecule Biosynthetic Process Transforming Growth Factor Beta Receptor Signaling Pathway Response To Growth Factor Positive Regulation Of Cellular Biosynthetic Process Kidney Epithelium Development SMAD Protein Complex Assembly Embryonic Pattern Specification Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Gene Silencing Positive Regulation Of Gene Expression Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Transcription, DNA-templated Posttranscriptional Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process Gene Silencing By RNA Macromolecule Biosynthetic Process Kidney Development Nucleobase-containing Compound Metabolic Process Renal System Development BMP Signaling Pathway Positive Regulation Of Cellular Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Primary MiRNA Processing Enzyme Linked Receptor Protein Signaling Pathway Cellular Nitrogen Compound Metabolic Process Urogenital System Development Gene Expression Gene Silencing By MiRNA Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process Posttranscriptional Gene Silencing Nitrogen Compound Metabolic Process Pattern Specification Process Biosynthetic Process Regulation Of Cell Differentiation Regulation Of Gene Expression Positive Regulation Of Cell Morphogenesis Involved In Differentiation Positive Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription	Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Membrane Organization Ephrin Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Golgi To Endosome Transport Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Defense Response To Virus By Virus Protein Transport Endosomal Transport Endocytosis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Establishment Of Protein Localization Cytoplasmic Transport Intracellular Transport Golgi Vesicle Transport Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Transport Cell Surface Receptor Signaling Pathway Organelle Organization Protein Localization Establishment Of Localization In Cell Response To Stimulus Axon Guidance Negative Regulation Of Signal Transduction Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Defense Response To Virus Negative Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Protein K33-linked Ubiquitination Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Signaling Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Adherens Junction Organization Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Locomotion Cellular Localization Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Immune System Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Axonogenesis Viral Process Negative Regulation Of MRNA 3'-end Processing Cellular Response To Progesterone Stimulus Axon Development Cell Morphogenesis Involved In Neuron Differentiation Cellular Response To Stimulus Chemotaxis
Tagcloud ?		antiproliferative apro article autoimmune biomarker disorders diverse dorsal embryonic emphasis erbb2 experimental functions helper humans immune implicated implications linking member molecule mounted recently reviews sclerosis th17 transducer types underscoring
Tagcloud (Difference) ?		antiproliferative apro article autoimmune biomarker disorders diverse dorsal embryonic emphasis erbb2 experimental functions helper humans immune implicated implications linking member molecule mounted recently reviews sclerosis th17 transducer types underscoring
Tagcloud (Intersection) ?