YAF2 and RING1

Number of citations of the paper that reports this interaction (PMID 22325352)
61

Data Source:
BioGRID (two hybrid, affinity chromatography technology, affinity chromatography technology)

		YAF2	RING1
Gene Name		YY1 associated factor 2	ring finger protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Sex Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Speck PcG Protein Complex PRC1 Complex
	Molecular Function	Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding	Chromatin Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated	Transcription, DNA-templated Anterior/posterior Pattern Specification Histone H2A Monoubiquitination Negative Regulation Of Transcription, DNA-templated Camera-type Eye Morphogenesis
Pathways			Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS			Wegener's granulomatosis ( 23740775)
Protein-Protein Interactions		6 interactors: GABPB1 MYCN RING1 SETBP1 YY1 ZFP42	31 interactors: APP BMI1 CBX4 CBX6 CBX7 CBX8 E2F6 ELAC2 FBXO38 FHL1 HIST3H3 PCGF1 PCGF2 PCGF3 PCGF5 PCGF6 PHC1 PIK3R3 RB1 RNF2 RYBP UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K USP7 YAF2
Entrez ID		10138	6015
HPRD ID		09606	03624
Ensembl ID		ENSG00000015153	ENSG00000204227
Uniprot IDs		Q8IY57	Q06587
PDB IDs		2D9G
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Camera-type Eye Morphogenesis Regulation Of Gene Expression Response To Prostaglandin F Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated Eye Morphogenesis RNA Biosynthetic Process Organ Morphogenesis Anterior/posterior Pattern Specification Organ Development Organelle Organization RNA Metabolic Process Regulation Of Genetic Imprinting Gene Expression Response To UV-C Camera-type Eye Development Cellular Macromolecule Biosynthetic Process Histone H2A Monoubiquitination Positive Regulation Of Gene Expression Macromolecule Biosynthetic Process Eye Development Histone H2A Ubiquitination Regulation Of Metabolic Process Negative Regulation Of Astrocyte Differentiation Pattern Specification Process Regulation Of Transcription From RNA Polymerase II Promoter System Development Spermatogenesis Male Gamete Generation Histone Monoubiquitination Cartilage Condensation Nucleobase-containing Compound Metabolic Process Sensory Organ Development Negative Regulation Of Cellular Metabolic Process Regulation Of Astrocyte Differentiation Multicellular Organismal Development Heterocycle Metabolic Process Gamete Generation Cellular Aromatic Compound Metabolic Process Biosynthetic Process Histone Ubiquitination Anatomical Structure Development Negative Regulation Of Glial Cell Differentiation Cellular Nitrogen Compound Metabolic Process Protein Monoubiquitination Anatomical Structure Morphogenesis	Protein Modification By Small Protein Conjugation Protein Ubiquitination Protein K48-linked Ubiquitination Histone Ubiquitination Chromatin Modification Chromatin Organization Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Polyubiquitination Negative Regulation Of Gene Expression Transcription, DNA-templated Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process RNA Metabolic Process Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Histone Modification Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Protein Monoubiquitination Nucleobase-containing Compound Metabolic Process Cellular Protein Modification Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Histone Monoubiquitination Regulation Of RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Protein K11-linked Ubiquitination Regulation Of Gene Expression Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Mitotic Cell Cycle Phase Transition Histone H2A Monoubiquitination Regulation Of Cell Cycle Phase Transition Cellular Protein Metabolic Process Regulation Of Metabolic Process Histone H2A Ubiquitination Organelle Organization Metabolic Process Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Proteasomal Protein Catabolic Process
Tagcloud ?		antagonized c2 calpain cdna cloning eliminated encodes finger fingers greatly isolation mapping message myoblasts myogenic normally potentiates promyogenic proteolysis proteolytic restricted reverses sarcomeric stimulates stimulatory termed x10 yy1 zinc	4h accomplish antioxidant ck cmv cortex creatine de dehydrogenase downregulated e3 electrophoresis extremely finger hselm lactate ldh ligase nontg secretase sel selenium selenoprotein selm spots synaptotagmin sytxv tg upregulated
Tagcloud (Difference) ?		antagonized c2 calpain cdna cloning eliminated encodes fingers greatly isolation mapping message myoblasts myogenic normally potentiates promyogenic proteolysis proteolytic restricted reverses sarcomeric stimulates stimulatory termed x10 yy1 zinc	4h accomplish antioxidant ck cmv cortex creatine de dehydrogenase downregulated e3 electrophoresis extremely hselm lactate ldh ligase nontg secretase sel selenium selenoprotein selm spots synaptotagmin sytxv tg upregulated
Tagcloud (Intersection) ?		finger