ACTR1B and DCTN1

Number of citations of the paper that reports this interaction (PMID 12857853)
17

Data Source:
HPRD (in vitro)

		ACTR1B	DCTN1
Gene Name		ARP1 actin-related protein 1 homolog B, centractin beta (yeast)	dynactin 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Dynactin Complex Membrane Extracellular Vesicular Exosome	Kinetochore Spindle Pole Cytoplasm Centrosome Cytosol Dynactin Complex Microtubule Membrane Dynein Complex Retromer Complex Cell Leading Edge
	Molecular Function	Protein Binding ATP Binding	Motor Activity Protein Binding Dynein Binding
	Biological Process	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Organelle Organization Mitotic Nuclear Division Nervous System Development Microtubule-based Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Endoplasmic Reticulum Unfolded Protein Response Melanosome Transport Retrograde Transport, Endosome To Golgi Cellular Protein Metabolic Process
Pathways		MHC class II antigen presentation Adaptive Immune System	IRE1alpha activates chaperones MHC class II antigen presentation XBP1(S) activates chaperone genes Unfolded Protein Response (UPR) Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ACTA1 APP CHD3 CSNK2B DCTN1 MAPK6 TK1 ZDHHC17	42 interactors: ACTR1A ACTR1B AKT1 APEX1 BBS1 BBS4 BICD1 BICD2 CASP2 CASP3 CASP7 CDC37 CLIP1 DCTN3 DISC1 DST DTNBP1 DYNC1I2 FBXL5 GRB2 GSK3B HAP1 KIAA0408 KIF11 MAP2K3 MAP2K6 MAPRE1 MED14 MTERF1 NEK2 PAFAH1B1 PFDN1 PGAM1 PPP1CA RAB6A RBL2 RPGR SEC23A SPTBN2 STAT1 VIM ZNF512B
Entrez ID		10120	1639
HPRD ID		05508	07206
Ensembl ID		ENSG00000115073	ENSG00000204843
Uniprot IDs		P42025	Q14203 Q6MZZ3
PDB IDs			1TXQ 2COY 2HKN 2HKQ 2HL3 2HL5 2HQH 3E2U 3TQ7
Enriched GO Terms of Interacting Partners?		Fetal Process Involved In Parturition Cell Cycle Skeletal Muscle Cell Proliferation Skeletal Muscle Fiber Adaptation Synaptic Growth At Neuromuscular Junction Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Movement Of Cell Or Subcellular Component Collateral Sprouting In Absence Of Injury Cell Growth Regulation Of Protein Kinase Activity Collateral Sprouting Axon Midline Choice Point Recognition Microtubule-based Process Regulation Of Kinase Activity Response To External Stimulus Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Response To Cortisol Thymidine Metabolic Process Phosphorylation Cellular Component Assembly Axon Choice Point Recognition Skeletal Muscle Thin Filament Assembly Positive Regulation Of Activin Receptor Signaling Pathway Deoxyribonucleoside Monophosphate Biosynthetic Process Adiponectin-activated Signaling Pathway Skeletal Myofibril Assembly Response To Hormone Neuron Remodeling Skeletal Muscle Adaptation Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Regulation Of Binding Response To Stimulus Endothelial Tube Morphogenesis Regulation Of Protein Phosphorylation Microtubule-based Movement Positive Regulation Of Cellular Protein Metabolic Process Response To Metal Ion System Development Response To Organic Substance Parturition Cellular Copper Ion Homeostasis Positive Regulation Of Protein Metabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Lipoprotein Transport Cellular Protein Metabolic Process Axon Guidance Magnesium Ion Transport Cellular Response To Stimulus	Cell Cycle Microtubule-based Process Organelle Organization Cell Cycle Process Mitotic Cell Cycle Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Microtubule-based Movement Microtubule-based Transport Regulation Of Cell Cycle Cytoskeleton-dependent Intracellular Transport Minus-end-directed Organelle Transport Along Microtubule Movement Of Cell Or Subcellular Component Mitotic Cell Cycle Process Regulation Of Microtubule-based Process Antigen Processing And Presentation Organelle Transport Along Microtubule Immune System Process Microtubule Cytoskeleton Organization G2/M Transition Of Mitotic Cell Cycle Regulation Of Cellular Component Organization Antigen Processing And Presentation Of Peptide Antigen Intracellular Transport Execution Phase Of Apoptosis Cellular Protein Localization Cytoskeleton Organization Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Protein Localization Cellular Localization Microtubule Anchoring At Microtubule Organizing Center Neurotrophin TRK Receptor Signaling Pathway Regulation Of Metabolic Process Neurotrophin Signaling Pathway Regulation Of Organelle Organization Establishment Of Localization In Cell Protein Localization To Cytoskeleton Cell Division Generation Of Neurons Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of Cilium Assembly Organelle Assembly Neurogenesis Mitotic Nuclear Division Anatomical Structure Development Regulation Of Cell Projection Organization Nervous System Development Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cell Cycle Process
Tagcloud ?			als2 c147r causative chmp2b dao diagnose f21c faces fig4 g148d g59r got haloplex optn pedigree pfn1 probands sanger segregate setx sigmar1 sod1 spg11 sqstm1 synonymous tardbp ubqln2 vapb vcp
Tagcloud (Difference) ?			als2 c147r causative chmp2b dao diagnose f21c faces fig4 g148d g59r got haloplex optn pedigree pfn1 probands sanger segregate setx sigmar1 sod1 spg11 sqstm1 synonymous tardbp ubqln2 vapb vcp
Tagcloud (Intersection) ?