ACTR1B

Description		actin related protein 1B
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Centrosome Microtubule Organizing Center Cytosol Cytoskeleton Dynactin Complex Membrane Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Nucleotide Binding Protein Binding ATP Binding
	Biological Process
Pathways		MHC class II antigen presentation Neutrophil degranulation
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Bipolar disorder ( 31043756) Bitter alcoholic beverage consumption ( 31046077) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		8 interacting genes: ACTA1 APP CHD3 CSNK2B DCTN1 MAPK6 TK1 ZDHHC17
Entrez ID		10120
HPRD ID		05508
Ensembl ID		ENSG00000115073
Uniprot IDs		P42025
PDB IDs
Enriched GO Terms of Interacting Partners?		Neuron Projection Maintenance Cell Body Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Signaling Receptor Binding Growth Cone Lamellipodium Neuron Projection Organization Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Synapse Organization Axo-dendritic Transport Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Protein Tetramerization Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Chromatin Binding Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization PML Body Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Cell Cortex Region Positive Regulation Of Neuromuscular Junction Development Septin Cytoskeleton DNA Synthesis Involved In Mitotic DNA Replication Thymidine Kinase Activity Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse ATP Binding Mesenchyme Migration Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Axonogenesis Low-density Lipoprotein Particle Mediated Signaling Release From Viral Latency
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