TSFM and RALBP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TSFM	RALBP1
Description		Ts translation elongation factor, mitochondrial	ralA binding protein 1
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GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Intracellular Organelle Lumen	Spindle Pole Nucleus Nucleoplasm Cytoplasm Mitochondrion Cytosol Cytoskeleton Plasma Membrane Membrane Nuclear Body
	Molecular Function	RNA Binding Translation Elongation Factor Activity Protein Binding	Nucleotide Binding GTPase Activator Activity Protein Binding ATP Binding ABC-type Xenobiotic Transporter Activity ABC-type Glutathione S-conjugate Transporter Activity Transmembrane Transporter Activity Small GTPase Binding ATPase-coupled Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity
	Biological Process	Translation Translational Elongation Mitochondrial Translational Elongation	Positive Regulation Of Protein Phosphorylation Receptor-mediated Endocytosis Chemotaxis Signal Transduction Small GTPase-mediated Signal Transduction Regulation Of Cdc42 Protein Signal Transduction Regulation Of GTPase Activity Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Transmembrane Transport Positive Regulation Of Mitochondrial Fission Doxorubicin Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane
Pathways		Mitochondrial translation elongation	CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases		Combined oxidative phosphorylation deficiency (COXPD)
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Brain morphology (MOSTest) ( 32665545) Multiple sclerosis ( 24076602)	LDL cholesterol ( 30275531)
Interacting Genes		12 interacting genes: CCDC89 CDC42 CEP70 CPLX2 DRC4 GOLGA6L9 KRTAP1-1 LIG4 MDFI MTRNR2L1 PPP1R12C RALBP1	46 interacting genes: AMOTL2 AP2M1 C1orf216 CASP8 CBY1 CCDC13 CCDC136 CCDC88B CCHCR1 CCNB1 CEP57 CREBZF DLG4 DRC4 FADD GSE1 HOOK2 HSF1 HSPA13 IKBKG ITSN1 KANK2 LDOC1 MSANTD4 PCM1 PLCG2 PPP1R13B PRKCA RAC1 RALA RALB REPS1 REPS2 RHOU SAPCD2 SMARCE1 SYCE1 SYNJ2BP TBRG1 TCP10L TNIP1 TP53BP2 TRAF2 TSFM ZBTB38 ZNF707
Entrez ID		10102	10928
HPRD ID		05285	09013
Ensembl ID		ENSG00000123297	ENSG00000017797
Uniprot IDs		E5KS95 P43897	Q15311
PDB IDs		2CP9	2KWH 2KWI 2MBG 6ZQT 6ZRN
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Macrophage Differentiation Regulation Of Macrophage Differentiation Regulation Of Endocytosis Protein-macromolecule Adaptor Activity Intracellular Signaling Cassette Endocytosis Cellular Component Assembly Protein Binding Intracellular Signal Transduction Positive Regulation Of Immune System Process Regulation Of Vesicle-mediated Transport Cytosol Positive Regulation Of Execution Phase Of Apoptosis Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of Receptor-mediated Endocytosis Protein Kinase Binding Cytoplasmic Microtubule Organization Import Into Cell Death Effector Domain Binding Regulation Of Signal Transduction Centrosome Regulation Of Receptor Internalization Protein-containing Complex Organization Tumor Necrosis Factor Receptor Binding Ripoptosome CD95 Death-inducing Signaling Complex Protein-containing Complex Assembly Cell Death Response To Lipopolysaccharide Death-inducing Signaling Complex Positive Regulation Of Leukocyte Differentiation Ubiquitin Protein Ligase Binding Programmed Cell Death Identical Protein Binding Positive Regulation Of Cellular Component Organization Tumor Necrosis Factor Receptor Superfamily Binding Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Myeloid Cell Differentiation Microtubule Cytoskeleton Organization Regulation Of Canonical NF-kappaB Signal Transduction Organelle Organization Apoptotic Signaling Pathway Positive Regulation Of Peptide Hormone Secretion TRAIL-activated Apoptotic Signaling Pathway Response To Molecule Of Bacterial Origin Positive Regulation Of Signal Transduction Positive Regulation Of Peptide Secretion Cytoskeleton Organization Regulation Of Cytokine Production
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