TSSC4 and RNF31

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TSSC4	RNF31
Gene Name		tumor suppressing subtransferable candidate 4	ring finger protein 31
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Cytoplasm Cytoplasmic Side Of Plasma Membrane CD40 Receptor Complex LUBAC Complex
	Molecular Function		Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Binding Ubiquitin Binding
	Biological Process		Protein Polyubiquitination CD40 Signaling Pathway Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling T Cell Receptor Signaling Pathway Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Linear Polyubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: APP CEP76 GMCL1 GOLGA2 KPNA3 REL RNF31 SPTAN1 TAB1 TCF4 TERF2IP TRAF1 TRAF2 UBA1	27 interactors: AES ATN1 ATXN1 ATXN7 AZI2 CCDC24 GFI1B IKBKG KIF1A KRTAP9-2 NOS3 NR0B1 NR0B2 PITX1 PRKCA RBCK1 SMAD3 SNRPC SOCS3 TRAF1 TRIM25 TSSC4 UBC UBE2D1 UBE2D3 VASN VCP
Entrez ID		10078	55072
HPRD ID		10357	11516
Ensembl ID		ENSG00000184281	ENSG00000092098
Uniprot IDs		Q9Y5U2	Q96EP0
PDB IDs			2CT7 4DBG 4JUY
Enriched GO Terms of Interacting Partners?		Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Protein Binding Positive Regulation Of Intracellular Signal Transduction I-kappaB Kinase/NF-kappaB Signaling Regulation Of Binding Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Regulation Of Signaling Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of RNA Metabolic Process NIK/NF-kappaB Signaling Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Gene Expression Positive Regulation Of Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of DNA Recombination At Telomere TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Protein Binding MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Cellular Response To Stimulus Response To Stimulus Innate Immune Response Toll-like Receptor 4 Signaling Pathway Synaptic Growth At Neuromuscular Junction Catenin Import Into Nucleus CD40 Signaling Pathway Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Viral Penetration Into Host Nucleus Cellular Response To Stress Response To Stress Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Collateral Sprouting In Absence Of Injury Protein Linear Polyubiquitination Toll-like Receptor Signaling Pathway Apoptotic Process Programmed Cell Death Positive Regulation Of Binding Immune Response-regulating Signaling Pathway Protein Import Into Nucleus Maintenance Of DNA Repeat Elements Nuclear Import See more	Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Signaling Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Signaling Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of RNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction Negative Regulation Of Nucleic Acid-templated Transcription Transcription, DNA-templated Negative Regulation Of RNA Biosynthetic Process DNA-templated Transcription, Initiation RNA Biosynthetic Process Gene Expression Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process RNA Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Response To Abiotic Stimulus Regulation Of Apoptotic Process MyD88-independent Toll-like Receptor Signaling Pathway Cellular Response To Organic Substance Toll-like Receptor 3 Signaling Pathway Regulation Of Cell Death Protein Ubiquitination Signaling Toll-like Receptor 4 Signaling Pathway Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Response To Organic Substance Protein Modification By Small Protein Conjugation Cell Communication Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Immune System Process Apoptotic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels See more
Tagcloud ?		11p15 beckwith bws caenorhabditis discover grc homologies hybrids imprinting kvlqt1 melanomas melastatin mlsn1 mtr1 neoplasias paternal pkd1 pkd2 polycystic predisposition resides rhabdoid rhabdomyosarcomas spanning trp trpc7 versions wiedemann wilms	adjuvant antiestrogens arise aromatase associates atypical confirms cytosol decreases diagnostics e3 eralpha establishes estrogen facilitates initially insights ligase mono occupied promoters reduces stability stabilizes stabilizing therapeutics ubiquitin ubiquitination utmost
Tagcloud (Difference) ?		11p15 beckwith bws caenorhabditis discover grc homologies hybrids imprinting kvlqt1 melanomas melastatin mlsn1 mtr1 neoplasias paternal pkd1 pkd2 polycystic predisposition resides rhabdoid rhabdomyosarcomas spanning trp trpc7 versions wiedemann wilms	adjuvant antiestrogens arise aromatase associates atypical confirms cytosol decreases diagnostics e3 eralpha establishes estrogen facilitates initially insights ligase mono occupied promoters reduces stability stabilizes stabilizing therapeutics ubiquitin ubiquitination utmost
Tagcloud (Intersection) ?