SOX21-AS1 and USP10

Number of citations of the paper that reports this interaction (PubMedID 36335356)
41

Data Source:
BioGRID (unspecified method, affinity chromatography technology)

		SOX21-AS1	USP10
Description		SOX21 antisense RNA 1	ubiquitin specific peptidase 10
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm Endosome Early Endosome Cytosol Cytosolic Ribosome Protein-containing Complex Intermediate Filament Cytoskeleton
	Molecular Function		P53 Binding RNA Binding Cysteine-type Endopeptidase Activity Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Hydrolase Activity Transmembrane Transporter Binding Molecular Function Inhibitor Activity
	Biological Process		DNA Repair Chromatin Remodeling Proteolysis Protein Monoubiquitination Autophagy DNA Damage Response Regulation Of Autophagy Protein Deubiquitination Translesion Synthesis DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Protein Stability Stress Granule Assembly Monoubiquitinated Protein Deubiquitination Negative Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of Stress Granule Assembly Cellular Response To Interleukin-1 Rescue Of Stalled Ribosome Ribosome-associated Ubiquitin-dependent Protein Catabolic Process
Pathways			Termination of translesion DNA synthesis Ub-specific processing proteases
Drugs
Diseases
GWAS			Appendicular lean mass ( 33097823) Copper levels ( 26025379) Height ( 18391951) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 32888494) Plasma factor VII activating protease levels ( 30070759) Response to mTOR inhibitor (everolimus) ( 24009623) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494)
Interacting Genes		1 interacting genes: USP10	32 interacting genes: AKT1 ANLN AR AXIN1 CCND3 CFTR CTNNB1 DAAM1 FSCN1 FZR1 G3BP1 G3BP2 H2AC20 HDAC6 HNRNPLL KLF4 LINC00460 MAP1LC3B MSH2 NOTCH1 PABPC1 PCGF5 RAD51 RUNX1 SCNN1A SCNN1G SMAD4 SNX3 SOX21-AS1 TRNAU1AP UBC ZBTB7A
Entrez ID		100507533	9100
HPRD ID			07029
Ensembl ID		ENSG00000227640	ENSG00000103194
Uniprot IDs			A0A7G6J4N4 Q14694
PDB IDs			7XHF 8TH6
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Stress Granule Assembly Monoubiquitinated Protein Deubiquitination Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Regulation Of Stress Granule Assembly Cellular Response To Interleukin-1 DNA Damage Response, Signal Transduction By P53 Class Mediator Stress Granule Assembly DNA Synthesis Involved In DNA Repair Postreplication Repair Intermediate Filament Cytoskeleton Translesion Synthesis Rescue Of Stalled Ribosome Molecular Function Inhibitor Activity Ribosome Disassembly Protein Monoubiquitination Translational Elongation Cysteine-type Endopeptidase Activity P53 Binding Negative Regulation Of Canonical NF-kappaB Signal Transduction DNA Biosynthetic Process Response To Interleukin-1 Cysteine-type Deubiquitinase Activity Organelle Disassembly Protein Deubiquitination Signal Transduction By P53 Class Mediator Cytosolic Ribosome Protein Modification By Small Protein Removal Cysteine-type Peptidase Activity Transmembrane Transporter Binding Signal Transduction In Response To DNA Damage	Transcription Corepressor Binding Positive Regulation Of Cellular Component Organization Enzyme Binding Response To Alcohol Epithelial Cell Differentiation Involved In Prostate Gland Development Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Negative Regulation Of Nucleobase-containing Compound Metabolic Process SMAD Binding Cellular Response To Oxygen-containing Compound Cellular Response To Hormone Stimulus Response To Ketone Negative Regulation Of Macromolecule Metabolic Process I-SMAD Binding Negative Regulation Of RNA Metabolic Process In Utero Embryonic Development Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cell Proliferation Involved In Heart Morphogenesis Chordate Embryonic Development Positive Regulation Of Gene Expression Epithelial Cell Differentiation Regulation Of Extracellular Matrix Organization Negative Regulation Of Metabolic Process Response To Lipid Embryo Development Ending In Birth Or Egg Hatching Multicellular Organism Development Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Axis Specification Regulation Of Cell Cycle Phase Transition Negative Regulation Of Macromolecule Biosynthetic Process Cytosol Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of Extracellular Matrix Organization Cell Cortex Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Multicellular Organismal-level Water Homeostasis Sensory Perception Of Salty Taste Negative Regulation Of Biosynthetic Process Regulation Of Wnt Signaling Pathway Positive Regulation Of Organelle Assembly Positive Regulation Of Epithelial Cell Proliferation Regulation Of Mitotic Cell Cycle Endocardial Cell Differentiation Positive Regulation Of Cellular Component Biogenesis Beta-catenin Binding Response To Mineralocorticoid Regulation Of Cell Cycle Process Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Regulation Of Protein Metabolic Process Regulation Of Cellular Component Organization Protein-containing Complex
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