MAILR and DDX42

Number of citations of the paper that reports this interaction (PubMedID 32241891)
64

Data Source:
BioGRID (unspecified method)

		MAILR	DDX42
Description		macrophage interferon regulatory lncRNA	DEAD-box helicase 42
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm Cytosol Cajal Body Membrane Nuclear Speck U2-type Prespliceosome
	Molecular Function		Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity
	Biological Process		Intracellular Protein Localization Regulation Of Apoptotic Process U2-type Prespliceosome Assembly
Pathways			mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS			Body mass index ( 25673413) Hemoglobin ( 32888494) Hip circumference adjusted for BMI ( 25673412)
Interacting Genes		17 interacting genes: ADRM1 BAZ1B CCAR2 CD109 CPSF7 DDX42 ELMO3 EXOC3 HLA-DRB1 IRF2BP2 MAP3K7 OPTN TIMM29 UBXN4 VAPB WEE1 YBX3	13 interacting genes: APP DHX15 FBXO25 LINC00624 MAILR MDM2 PRPF19 RECQL5 RNF10 SF3A1 SF3B4 SNRPC U2SURP
Entrez ID		100506753	11325
HPRD ID			09909
Ensembl ID			ENSG00000198231
Uniprot IDs			Q86XP3
PDB IDs			7EVN 8DPE 8HK1
Enriched GO Terms of Interacting Partners?		Histone Kinase Activity Response To Unfolded Protein	MRNA Splicing, Via Spliceosome Spliceosomal Complex RNA Splicing, Via Transesterification Reactions U2 SnRNP RNA Splicing Spliceosomal Complex Assembly MRNA Processing Protein-RNA Complex Assembly RNA Processing Response To Alkaloid Nucleic Acid Binding MRNA Metabolic Process U2-type Prespliceosome Protein-containing Complex Assembly U12-type Spliceosomal Complex U2-type Prespliceosome Assembly Amyloid Fibril Formation U2-type Spliceosomal Complex MRNA Splice Site Recognition Protein-containing Complex Organization Cellular Response To Alkaloid Macromolecule Metabolic Process Spliceosomal SnRNP Assembly Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Nucleus Response To Formaldehyde Cellular Response To Vitamin B1 U2-type Precatalytic Spliceosome Ubiquitin-protein Transferase Activity Protein Ubiquitination Protein Autoubiquitination Acetylcholine Receptor Activator Activity Lipoprotein Particle Regulation Of Receptor Internalization Positive Regulation Of Protein Import Protein Modification By Small Protein Conjugation Mitotic DNA-templated DNA Replication PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization
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