MAILR and CCAR2

Number of citations of the paper that reports this interaction (PubMedID 32241891)
64

Data Source:
BioGRID (unspecified method)

		MAILR	CCAR2
Description		macrophage interferon regulatory lncRNA	cell cycle and apoptosis regulator 2
Image		No pdb structure
GO Annotations	Cellular Component		Chromatin Nucleus Nucleoplasm Cytoplasm Mitochondrial Matrix Spindle Cytoskeleton DBIRD Complex
	Molecular Function		Adenyl-nucleotide Exchange Factor Activity RNA Polymerase II Complex Binding RNA Binding Enzyme Inhibitor Activity Protein Binding Enzyme Binding Unfolded Protein Binding
	Biological Process		Regulation Of DNA-templated Transcription MRNA Processing Apoptotic Process DNA Damage Response RNA Splicing Response To UV Wnt Signaling Pathway Negative Regulation Of Cell Growth Regulation Of Protein Stability Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of DNA-templated Transcription Elongation Regulation Of Circadian Rhythm Positive Regulation Of Apoptotic Process Negative Regulation Of Catalytic Activity Mitochondrial Fragmentation Involved In Apoptotic Process Negative Regulation Of DNA-templated Transcription Rhythmic Process Positive Regulation Of Canonical Wnt Signaling Pathway Regulation Of Protein Deacetylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of DNA Damage Checkpoint
Pathways			Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS			Haemorrhoidal disease ( 33888516)
Interacting Genes		17 interacting genes: ADRM1 BAZ1B CCAR2 CD109 CPSF7 DDX42 ELMO3 EXOC3 HLA-DRB1 IRF2BP2 MAP3K7 OPTN TIMM29 UBXN4 VAPB WEE1 YBX3	20 interacting genes: AR BAG2 CEBPA FMR1 FXR1 FXR2 HTRA2 IKBKB MAILR MALAT1 MYC NLGN3 RNF10 SIAH2 SIRT1 SUCLG1 SUMO2 TRIM28 WDR3 ZNF335
Entrez ID		100506753	57805
HPRD ID			09159
Ensembl ID			ENSG00000158941
Uniprot IDs			Q8N163
PDB IDs			8EZ6
Enriched GO Terms of Interacting Partners?		Histone Kinase Activity Response To Unfolded Protein	Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Positive Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Metabolic Process Regulation Of Multicellular Organismal Development Translation Regulator Activity Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Development Positive Regulation Of Catabolic Process Regulation Of Developmental Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Differentiation Positive Regulation Of Proteolysis Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Multicellular Organismal Process Presynapse Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Developmental Process Regulation Of Nervous System Development Negative Regulation Of Metabolic Process RNA Strand Annealing Activity Positive Regulation Of Nervous System Development Presynaptic Modulation Of Chemical Synaptic Transmission Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Multicellular Organismal Process Positive Regulation Of Protein Metabolic Process Molecular Condensate Scaffold Activity Intracellular Membraneless Organelle Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Cell Differentiation Protein Heterodimerization Activity Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Ubiquitin-dependent Protein Catabolic Process Euchromatin Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Neurogenesis Protein Catabolic Process Regulation Of Protein Catabolic Process
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