MAILR and BAZ1B

Number of citations of the paper that reports this interaction (PubMedID 32241891)
64

Data Source:
BioGRID (unspecified method)

		MAILR	BAZ1B
Description		macrophage interferon regulatory lncRNA	bromodomain adjacent to zinc finger domain 1B
Image		No pdb structure
GO Annotations	Cellular Component		Chromatin Condensed Chromosome Nucleus Nucleoplasm Pericentric Heterochromatin Nucleolus Nuclear Replication Fork WICH Complex B-WICH Complex
	Molecular Function		Nucleotide Binding Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Zinc Ion Binding Kinase Activity Transferase Activity Histone Kinase Activity Histone Binding Metal Ion Binding Histone H2AXY142 Kinase Activity
	Biological Process		Chromatin Organization Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II DNA Damage Response Post-translational Protein Modification Positive Regulation Of Transcription By RNA Polymerase I Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase III Negative Regulation Of Mitotic Chromosome Condensation
Pathways			B-WICH complex positively regulates rRNA expression Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Drugs
Diseases
GWAS			C-reactive protein levels or HDL-cholesterol levels (pleiotropy) ( 27286809) Hip index ( 34021172) Hypertriglyceridemia ( 23505323) Hyperuricemia ( 29124443) Lamb consumption ( 32066663) Lipoprotein (a) levels ( 33730874) Malaria ( 31844061) Meat-related diet ( 32066663) Metabolic syndrome ( 31589552) Migraine ( 27182965) Non-oily fish consumption ( 32066663) Platelet count ( 32888494) Protein C levels ( 20802025) Pursuit maintenance gain ( 29064472) Serum alkaline phosphatase levels ( 33339817) Serum uric acid levels ( 30993211) Triglyceride levels ( 32203549) Triglyceride levels x fish oil supplementation interaction (2df) ( 33760818) Triglycerides ( 20864672) Urate levels ( 31985003 23263486) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes		17 interacting genes: ADRM1 BAZ1B CCAR2 CD109 CPSF7 DDX42 ELMO3 EXOC3 HLA-DRB1 IRF2BP2 MAP3K7 OPTN TIMM29 UBXN4 VAPB WEE1 YBX3	16 interacting genes: CDT1 H2AX KANSL1 KAT8 MAILR MTNR1A MYO1C NR4A2 PCNA RNF10 SIRT1 SMARCA1 SMARCA5 SMARCC2 SMARCE1 SUMO2
Entrez ID		100506753	9031
HPRD ID			10416
Ensembl ID			ENSG00000009954
Uniprot IDs			Q9UIG0
PDB IDs			1F62 5NNF
Enriched GO Terms of Interacting Partners?		Histone Kinase Activity Response To Unfolded Protein	Positive Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Organization Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of DNA Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Remodeling Positive Regulation Of RNA Metabolic Process Regulation Of DNA Metabolic Process Positive Regulation Of DNA Repair Heterochromatin Formation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Kinetochore Negative Regulation Of Gene Expression, Epigenetic Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Nucleoplasm Regulation Of Primary Metabolic Process Positive Regulation Of Double-strand Break Repair Chromatin Regulation Of DNA Repair Regulation Of RNA Metabolic Process Epigenetic Regulation Of Gene Expression CERF Complex Nucleosome Organization Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Metabolic Process Positive Regulation Of DNA Replication Nucleosome Array Spacer Activity Regulation Of Double-strand Break Repair Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Histone Binding NURF Complex RDNA Heterochromatin Formation Negative Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Chromosome B-WICH Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle Process Negative Regulation Of Metabolic Process BBAF Complex Regulation Of Mitochondrial Transcription Negative Regulation Of Macromolecule Biosynthetic Process Chromatin Silencing Complex
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