NAT8

Gene Name		N-acetyltransferase 8 (GCN5-related, putative)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Integral Component Of Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Extracellular Vesicular Exosome
	Molecular Function	Lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Protein Binding Cysteine-S-conjugate N-acetyltransferase Activity
	Biological Process	Glutathione Metabolic Process Positive Regulation Of Gene Expression Peptidyl-lysine N6-acetylation Response To Drug Negative Regulation Of Apoptotic Process Beta-amyloid Metabolic Process
Pathways
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Creatinine levels ( 20383145) Glomerular filtration rate ( 23535967) Metabolic traits ( 21886157) Metabolite levels ( 21931564)
Protein-protein Interactions		2 interactors: SMAD4 TGFBR1
Entrez ID		9027
HPRD ID		08413
Ensembl ID		ENSG00000144035
Uniprot IDs		Q9UHE5
PDB IDs
Enriched GO Terms of Interacting Partners?		Endothelial Cell Activation Positive Regulation Of SMAD Protein Import Into Nucleus Regulation Of SMAD Protein Import Into Nucleus Cardiac Epithelial To Mesenchymal Transition Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Epithelial To Mesenchymal Transition Regulation Of Epithelial To Mesenchymal Transition Neuron Fate Commitment Positive Regulation Of Protein Import Into Nucleus Palate Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Mesenchymal Cell Development Mesenchymal Cell Differentiation Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Import Into Nucleus Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Response To Growth Factor Stimulus Response To Transforming Growth Factor Beta Regulation Of Protein Localization To Nucleus Mesenchyme Development Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Heart Morphogenesis Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Intracellular Transport Stem Cell Development Anterior/posterior Pattern Specification Regulation Of Binding Regulation Of Intracellular Protein Transport Cell Fate Commitment Nephrogenic Mesenchyme Morphogenesis Kidney Development Stem Cell Differentiation Renal System Development Positive Regulation Of Protein Transport Regulation Of Cell Growth Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis Urogenital System Development Regulation Of Intracellular Transport Regulation Of Cell Morphogenesis Pattern Specification Process Gland Development Endocardial Cell Differentiation In Utero Embryonic Development Heart Development
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