NAT8 and SSB

		NAT8	SSB
Description		N-acetyltransferase 8 (putative)	small RNA binding exonuclease protection factor La
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Chromosome, Telomeric Region Nucleus Cytoplasm Cytosol Cytoplasmic Stress Granule Ribonucleoprotein Complex
	Molecular Function	L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Protein Binding N-acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups L-cysteine-S-conjugate N-acetyltransferase Activity Protein-lysine-acetyltransferase Activity	TRNA Binding Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Poly(U) RNA Binding Sequence-specific MRNA Binding
	Biological Process	Glutathione Metabolic Process Positive Regulation Of Gene Expression Peptidyl-lysine N6-acetylation Amyloid Fibril Formation	TRNA 5'-leader Removal RNA Processing TRNA Modification TRNA Export From Nucleus TRNA Processing Histone MRNA Metabolic Process TRNA 3'-end Processing Positive Regulation Of Translation Nuclear Histone MRNA Catabolic Process IRES-dependent Viral Translational Initiation Protein Localization To Cytoplasmic Stress Granule
Pathways		Amyloid fiber formation	RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Creatinine levels ( 20383145) Estimated glomerular filtration rate ( 31015462 30604766) Glomerular filtration rate ( 23535967) Glomerular filtration rate (creatinine) ( 28452372) Hemoglobin levels ( 32327693) Macrovascular complications in type 2 diabetes ( 33430853) Metabolic traits ( 21886157) Metabolite levels ( 21931564) Metabolite levels (X-11787) ( 23934736) Serum metabolite concentrations in chronic kidney disease ( 33838163 29545352) Serum metabolite levels ( 33031748 24625756 23093944) Urinary metabolite levels in chronic kidney disease ( 29545352 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995) Urinary metabolite ratios in chronic kidney disease ( 29545352) Urinary metabolites ( 26352407)	Common carotid intima-media thickness in HIV infection ( 29206233) Fasting glucose change (long-term) ( 31263163) Glomerular filtration rate in diabetes ( 29703844)
Interacting Genes		31 interacting genes: AQP6 ARL13B ATP6V0E1 BIK CD79A CERS4 CREB3L1 EBP FAM209A FFAR2 GOLT1A GPR152 HSD17B13 JPH1 LEPROTL1 LMNA MTIF3 REEP2 SAR1A SLC10A6 SLC71A2 SMAD4 TGFBR1 TLCD4 TMEM143 TMEM14B TMEM31 TMX2 TRIM21 TSPAN31 YIPF4	14 interacting genes: APP CDC42 CEBPA CSNK2A1 CSNK2B GZMH H19 HMGA1 IL7R NCL OGT PTEN SPIB SPP1
Entrez ID		9027	6741
HPRD ID		08413	00168
Ensembl ID		ENSG00000144035	ENSG00000138385
Uniprot IDs		Q9UHE5	P05455
PDB IDs			1OWX 1S79 1S7A 1YTY 1ZH5 2VOD 2VON 2VOO 2VOP
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum	Regulation Of Proteolysis Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Positive Regulation Of Macromolecule Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Neuron Projection Organization Positive Regulation Of Macromolecule Biosynthetic Process Macrophage Differentiation Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Protein Catabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Proteolysis Positive Regulation Of RNA Biosynthetic Process Regulation Of Cell Population Proliferation Positive Regulation Of DNA-templated Transcription Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of RNA Metabolic Process Response To Cytokine Response To Peptide Positive Regulation Of Nucleobase-containing Compound Metabolic Process Dendritic Spine Morphogenesis PML Body Negative Regulation Of Protein Metabolic Process Regulation Of Growth Regulation Of Protein Metabolic Process Mononuclear Cell Differentiation Negative Regulation Of Protein Catabolic Process Sin3-type Complex Regulation Of Macromolecule Metabolic Process Positive Regulation Of Signal Transduction Molecular Function Activator Activity Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Proteolysis Leukocyte Differentiation Myeloid Leukocyte Differentiation Response To Nutrient PcG Protein Complex Regulation Of Gene Expression Negative Regulation Of Cell Population Proliferation Amyloid Fibril Formation Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Excitatory Postsynaptic Potential
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