NAT8 and NAT8B

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology)

		NAT8	NAT8B
Description		N-acetyltransferase 8 (putative)	N-acetyltransferase 8B (putative, gene/pseudogene)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Protein Binding N-acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups L-cysteine-S-conjugate N-acetyltransferase Activity Protein-lysine-acetyltransferase Activity	L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Protein Binding N-acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Protein-lysine-acetyltransferase Activity
	Biological Process	Glutathione Metabolic Process Positive Regulation Of Gene Expression Peptidyl-lysine N6-acetylation Amyloid Fibril Formation	Gastrulation With Mouth Forming Second Positive Regulation Of Gene Expression Regulation Of Macroautophagy Peptidyl-lysine N6-acetylation Negative Regulation Of Apoptotic Process Amyloid-beta Metabolic Process Regulation Of Reticulophagy Amyloid Fibril Formation
Pathways		Amyloid fiber formation
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Creatinine levels ( 20383145) Estimated glomerular filtration rate ( 31015462 30604766) Glomerular filtration rate ( 23535967) Glomerular filtration rate (creatinine) ( 28452372) Hemoglobin levels ( 32327693) Macrovascular complications in type 2 diabetes ( 33430853) Metabolic traits ( 21886157) Metabolite levels ( 21931564) Metabolite levels (X-11787) ( 23934736) Serum metabolite concentrations in chronic kidney disease ( 33838163 29545352) Serum metabolite levels ( 33031748 24625756 23093944) Urinary metabolite levels in chronic kidney disease ( 29545352 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995) Urinary metabolite ratios in chronic kidney disease ( 29545352) Urinary metabolites ( 26352407)	Blood metabolite levels ( 26401656) Chronic kidney disease ( 20383146) Creatinine levels ( 20383145) Serum metabolite levels ( 23093944 33031748)
Interacting Genes		31 interacting genes: AQP6 ARL13B ATP6V0E1 BIK CD79A CERS4 CREB3L1 EBP FAM209A FFAR2 GOLT1A GPR152 HSD17B13 JPH1 LEPROTL1 LMNA MTIF3 REEP2 SAR1A SLC10A6 SLC71A2 SMAD4 TGFBR1 TLCD4 TMEM143 TMEM14B TMEM31 TMX2 TRIM21 TSPAN31 YIPF4
Entrez ID		9027	51471
HPRD ID		08413	12188
Ensembl ID		ENSG00000144035
Uniprot IDs		Q9UHE5
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum	L-cysteine-S-conjugate N-acetyltransferase Activity Peptidyl-lysine N6-acetylation Internal Protein Amino Acid Acetylation Internal Peptidyl-lysine Acetylation L-lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor Peptidyl-lysine Acetylation N-acetyltransferase Activity Protein-lysine-acetyltransferase Activity Amyloid Fibril Formation Protein Acetylation Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Glutathione Metabolic Process Endoplasmic Reticulum-Golgi Intermediate Compartment Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Acyltransferase Activity Modified Amino Acid Metabolic Process Sulfur Compound Metabolic Process
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