DNAJC7 and UBE4B

Number of citations of the paper that reports this interaction (PubMedID 15189447)
29

Data Source:
HPRD (two hybrid)

		DNAJC7	UBE4B
Description		DnaJ heat shock protein family (Hsp40) member C7	ubiquitination factor E4B
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Membrane Extracellular Exosome	Ubiquitin Ligase Complex Nucleus Cytoplasm
	Molecular Function	ATPase Activator Activity Protein Binding Heat Shock Protein Binding	Enzyme Binding Ubiquitin-ubiquitin Ligase Activity ATPase Binding
	Biological Process	Protein Folding Regulation Of Catalytic Activity Chaperone Cofactor-dependent Protein Refolding Regulation Of Cellular Response To Heat	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Granzyme-mediated Apoptotic Signaling Pathway Response To UV Ubiquitin-dependent ERAD Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS		Major depressive disorder x sex interaction ( 34099189)	Atrial fibrillation ( 29892015) Hemoglobin levels ( 33491795) Hepatocellular carcinoma ( 20676096) Hip circumference adjusted for BMI ( 34021172) Resting heart rate ( 27798624)
Interacting Genes		13 interacting genes: DISC1 HSP90AA1 HUS1 MKNK1 NF1 OGT RAD1 RAD9A SMAD2 SMAD9 SMURF1 TP53 UBE4B	24 interacting genes: ATXN3 CASP3 CASP6 CASP7 CDKN2A CNTN2 DNAJC7 ESR1 ETF1 FEZ1 GZMB HGS HRAS MAPK3 OTUB1 PGAM5 PPP3CA PRMT1 RAD23A TRIP12 UBE2D2 UBE2D3 VAV2 VCP
Entrez ID		7266	10277
HPRD ID		07046	11659
Ensembl ID		ENSG00000168259	ENSG00000130939
Uniprot IDs		Q99615	O95155
PDB IDs			2KRE 3L1X 3L1Z 5O75
Enriched GO Terms of Interacting Partners?
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