DNAJC7 and MKNK1

Number of citations of the paper that reports this interaction (PubMedID 20936779)
88

Data Source:
BioGRID (two hybrid)

		DNAJC7	MKNK1
Description		DnaJ heat shock protein family (Hsp40) member C7	MAPK interacting serine/threonine kinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Membrane Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	ATPase Activator Activity Protein Binding Heat Shock Protein Binding	Protein Serine/threonine Kinase Activity Calmodulin-dependent Protein Kinase Activity Protein Binding Calmodulin Binding ATP Binding Calcium-dependent Protein Serine/threonine Kinase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Protein Folding Regulation Of Catalytic Activity Chaperone Cofactor-dependent Protein Refolding Regulation Of Cellular Response To Heat	Regulation Of Translation Protein Phosphorylation Peptidyl-serine Phosphorylation Intracellular Signal Transduction Protein Autophosphorylation
Pathways		Regulation of HSF1-mediated heat shock response	Spry regulation of FGF signaling
Drugs			Fostamatinib
Diseases
GWAS		Major depressive disorder x sex interaction ( 34099189)	Schizophrenia ( 26198764) Triglyceride levels ( 31170924)
Interacting Genes		13 interacting genes: DISC1 HSP90AA1 HUS1 MKNK1 NF1 OGT RAD1 RAD9A SMAD2 SMAD9 SMURF1 TP53 UBE4B	27 interacting genes: APP ATXN3 CREBBP CREM DDAH2 DNAJC7 EIF4E EIF4G1 EIF4G2 EIF4G3 FANCA HGS HIPK2 HSP90AB1 MAPK1 MAPK14 MAPK3 MBP PABPC4 PAK2 PHAX PLA2G4A PRKDC RCN3 SPRY2 TNIP2 UBE2D1
Entrez ID		7266	8569
HPRD ID		07046	09468
Ensembl ID		ENSG00000168259	ENSG00000079277
Uniprot IDs		Q99615	A8K341 Q7Z319 Q9BUB5
PDB IDs			2HW6 2Y9Q 5WVD
Enriched GO Terms of Interacting Partners?
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