UBE4B and FEZ1

Number of citations of the paper that reports this interaction (PubMedID 15466860)
22

Data Source:
BioGRID (enzymatic study)

		UBE4B	FEZ1
Description		ubiquitination factor E4B	fasciculation and elongation protein zeta 1
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Cytoplasm	Cytoplasm Mitochondrion Golgi Apparatus Centrosome Microtubule Plasma Membrane Axon Dendrite Growth Cone Neuronal Cell Body
	Molecular Function	Enzyme Binding Ubiquitin-ubiquitin Ligase Activity ATPase Binding	Protein Kinase C Binding Protein Binding Gamma-tubulin Binding Protein N-terminus Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Granzyme-mediated Apoptotic Signaling Pathway Response To UV Ubiquitin-dependent ERAD Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Cell Adhesion Nervous System Development Axon Guidance Positive Regulation Of Neuron Projection Development Hippocampus Development Establishment Of Cell Polarity Positive Regulation Of Neuron Differentiation Establishment Of Mitochondrion Localization Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Mitochondrion Morphogenesis Cellular Response To Growth Factor Stimulus Negative Regulation Of Autophagosome Assembly
Pathways
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Hemoglobin levels ( 33491795) Hepatocellular carcinoma ( 20676096) Hip circumference adjusted for BMI ( 34021172) Resting heart rate ( 27798624)	Alanine aminotransferase levels ( 34315874) Aspartate aminotransferase levels ( 34315874) Breast cancer (survival) ( 25890600) Schizophrenia ( 22688191 23894747)
Interacting Genes		24 interacting genes: ATXN3 CASP3 CASP6 CASP7 CDKN2A CNTN2 DNAJC7 ESR1 ETF1 FEZ1 GZMB HGS HRAS MAPK3 OTUB1 PGAM5 PPP3CA PRMT1 RAD23A TRIP12 UBE2D2 UBE2D3 VAV2 VCP	57 interacting genes: BARD1 BORA BRD1 C8orf33 CCL7 CEP126 CIB1 CLASP2 COL9A2 CSTF2 DIS3L2 DISC1 DNAAF5 DRAP1 FEZ2 GEMIN7 GTF2F1 HAP1 HTATSF1 HTT IMMT LRIF1 MEST NBR1 NDUFB9 NEK1 OLFML3 P4HB PAM16 PDCD7 PPP4R3B PRKCZ PTH PTN PTPRS RAB3GAP1 RAB3GAP2 RAI14 RIF1 SAP30L SCOC SERPINH1 SMARCD1 SMC3 STAR TAC3 TAF1D TAF9 TBC1D25 TEDC2 TLK2 TOMM20 TTR TXNDC9 UBE4B WWC1 ZNF251
Entrez ID		10277	9638
HPRD ID		11659	09212
Ensembl ID		ENSG00000130939	ENSG00000149557
Uniprot IDs		O95155	Q99689
PDB IDs		2KRE 3L1X 3L1Z 5O75
Enriched GO Terms of Interacting Partners?
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