UBE4B and CNTN2

Number of citations of the paper that reports this interaction (PubMedID 33362245)
3

Data Source:
BioGRID (enzymatic study)

		UBE4B	CNTN2
Description		ubiquitination factor E4B	contactin 2
Image
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Cytoplasm	Plasma Membrane Cell Surface Axon Node Of Ranvier Neuronal Cell Body Myelin Sheath Juxtaparanode Region Of Axon Synapse Anchored Component Of Postsynaptic Membrane
	Molecular Function	Enzyme Binding Ubiquitin-ubiquitin Ligase Activity ATPase Binding	Protein Binding Carbohydrate Binding Identical Protein Binding Protein Self-association Cell-cell Adhesion Mediator Activity
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Granzyme-mediated Apoptotic Signaling Pathway Response To UV Ubiquitin-dependent ERAD Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Microtubule Cytoskeleton Organization Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Axonal Fasciculation Learning Adult Walking Behavior Regulation Of Cell Morphogenesis Involved In Differentiation Positive Regulation Of Protein Processing Cerebral Cortex GABAergic Interneuron Migration Central Nervous System Myelination Regulation Of Axon Diameter Receptor Internalization Clustering Of Voltage-gated Potassium Channels Negative Regulation Of Neuron Differentiation Regulation Of Neuronal Synaptic Plasticity Regulation Of Astrocyte Differentiation Positive Regulation Of Adenosine Receptor Signaling Pathway Dendrite Self-avoidance Protein Localization To Juxtaparanode Region Of Axon Establishment Of Protein Localization To Juxtaparanode Region Of Axon Presynaptic Membrane Organization
Pathways			L1CAM interactions NCAM1 interactions NrCAM interactions
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Hemoglobin levels ( 33491795) Hepatocellular carcinoma ( 20676096) Hip circumference adjusted for BMI ( 34021172) Resting heart rate ( 27798624)	Adventurousness ( 30643258) Aspartate aminotransferase levels ( 33547301) Blood protein levels ( 30072576 29875488 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) HDL cholesterol levels ( 32203549) Mean platelet volume ( 24026423) Meat-related diet ( 32066663) Number of sexual partners ( 30643258) Periodontitis (stage III/IV grade C) ( 33745150) Red blood cell count ( 27863252) Schizophrenia ( 30285260) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		24 interacting genes: ATXN3 CASP3 CASP6 CASP7 CDKN2A CNTN2 DNAJC7 ESR1 ETF1 FEZ1 GZMB HGS HRAS MAPK3 OTUB1 PGAM5 PPP3CA PRMT1 RAD23A TRIP12 UBE2D2 UBE2D3 VAV2 VCP	13 interacting genes: CDK4 CHEK1 CNTN1 CNTNAP2 EGFR L1CAM NCAN NEK2 NFYB NRCAM TUBG1 UBE4B VAC14
Entrez ID		10277	6900
HPRD ID		11659	01826
Ensembl ID		ENSG00000130939	ENSG00000184144
Uniprot IDs		O95155	A1L3A3 A1ML24 Q02246
PDB IDs		2KRE 3L1X 3L1Z 5O75	2OM5
Enriched GO Terms of Interacting Partners?
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