UBE4B and DNAJC7

Number of citations of the paper that reports this interaction (PubMedID 15189447)
29

Data Source:
HPRD (two hybrid)

		UBE4B	DNAJC7
Description		ubiquitination factor E4B	DnaJ heat shock protein family (Hsp40) member C7
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Cytoplasm	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Membrane Extracellular Exosome
	Molecular Function	Enzyme Binding Ubiquitin-ubiquitin Ligase Activity ATPase Binding	ATPase Activator Activity Protein Binding Heat Shock Protein Binding
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Granzyme-mediated Apoptotic Signaling Pathway Response To UV Ubiquitin-dependent ERAD Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Protein Folding Regulation Of Catalytic Activity Chaperone Cofactor-dependent Protein Refolding Regulation Of Cellular Response To Heat
Pathways			Regulation of HSF1-mediated heat shock response
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Hemoglobin levels ( 33491795) Hepatocellular carcinoma ( 20676096) Hip circumference adjusted for BMI ( 34021172) Resting heart rate ( 27798624)	Major depressive disorder x sex interaction ( 34099189)
Interacting Genes		24 interacting genes: ATXN3 CASP3 CASP6 CASP7 CDKN2A CNTN2 DNAJC7 ESR1 ETF1 FEZ1 GZMB HGS HRAS MAPK3 OTUB1 PGAM5 PPP3CA PRMT1 RAD23A TRIP12 UBE2D2 UBE2D3 VAV2 VCP	13 interacting genes: DISC1 HSP90AA1 HUS1 MKNK1 NF1 OGT RAD1 RAD9A SMAD2 SMAD9 SMURF1 TP53 UBE4B
Entrez ID		10277	7266
HPRD ID		11659	07046
Ensembl ID		ENSG00000130939	ENSG00000168259
Uniprot IDs		O95155	Q99615
PDB IDs		2KRE 3L1X 3L1Z 5O75
Enriched GO Terms of Interacting Partners?
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