SPRYD7 and PDZD3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

		SPRYD7	PDZD3
Description		SPRY domain containing 7	PDZ domain containing 3
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GO Annotations	Cellular Component		Cytosol Brush Border Apical Plasma Membrane Apical Junction Complex Apical Part Of Cell
	Molecular Function	Protein Binding	Protein Binding Protein C-terminus Binding Ion Channel Inhibitor Activity Guanylate Cyclase Inhibitor Activity Protein-membrane Adaptor Activity Ubiquitin-specific Protease Binding
	Biological Process		Ion Transport Water Transport Receptor Guanylyl Cyclase Signaling Pathway Response To Toxic Substance Negative Regulation Of CGMP-mediated Signaling Negative Regulation Of Guanylate Cyclase Activity Protein Localization To Plasma Membrane
Pathways			Intestinal infectious diseases
Drugs
Diseases
GWAS		Waist-to-hip ratio adjusted for body mass index ( 28430825)
Interacting Genes		14 interacting genes: AGXT AQP1 CAMK2B HEMK1 NTAQ1 OTX1 PDZD3 POGZ TLX3 TRIM55 TRIM63 TRIP13 VAC14 YPEL3	21 interacting genes: ABCC2 ASAP3 CACNA1S CFTR FCER1G GUCY2C NLRX1 NOMO1 PTGIR SLC15A1 SLC15A2 SLC22A3 SLC22A4 SLC22A5 SLC22A9 SLC41A3 SLCO1A2 SLCO1C1 SLCO3A1 SPRYD7 TAS2R8
Entrez ID		57213	79849
HPRD ID		08486	06191
Ensembl ID		ENSG00000123178	ENSG00000172367
Uniprot IDs		A0A024RDT6 Q5W111	B0YJ61 Q86UT5
PDB IDs		7CCB	2V90
Enriched GO Terms of Interacting Partners?
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