PDZD3 and TAS2R8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PDZD3	TAS2R8
Description		PDZ domain containing 3	taste 2 receptor member 8
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Brush Border Apical Plasma Membrane Apical Junction Complex Apical Part Of Cell	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Protein C-terminus Binding Ion Channel Inhibitor Activity Guanylate Cyclase Inhibitor Activity Protein-membrane Adaptor Activity Ubiquitin-specific Protease Binding	G Protein-coupled Receptor Activity Protein Binding Taste Receptor Activity Bitter Taste Receptor Activity
	Biological Process	Ion Transport Water Transport Receptor Guanylyl Cyclase Signaling Pathway Response To Toxic Substance Negative Regulation Of CGMP-mediated Signaling Negative Regulation Of Guanylate Cyclase Activity Protein Localization To Plasma Membrane	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste G Protein-coupled Receptor Signaling Pathway
Pathways		Intestinal infectious diseases	G alpha (i) signalling events Class C/3 (Metabotropic glutamate/pheromone receptors)
Drugs
Diseases
GWAS
Interacting Genes		21 interacting genes: ABCC2 ASAP3 CACNA1S CFTR FCER1G GUCY2C NLRX1 NOMO1 PTGIR SLC15A1 SLC15A2 SLC22A3 SLC22A4 SLC22A5 SLC22A9 SLC41A3 SLCO1A2 SLCO1C1 SLCO3A1 SPRYD7 TAS2R8	1 interacting genes: PDZD3
Entrez ID		79849	50836
HPRD ID		06191	16072
Ensembl ID		ENSG00000172367	ENSG00000121314
Uniprot IDs		B0YJ61 Q86UT5	Q9NYW2
PDB IDs		2V90
Enriched GO Terms of Interacting Partners?
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