PDZD3 and SLCO3A1

Number of citations of the paper that reports this interaction (PubMedID 15553237)
13

Data Source:
HPRD (two hybrid)

		PDZD3	SLCO3A1
Description		PDZ domain containing 3	solute carrier organic anion transporter family member 3A1
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Brush Border Apical Plasma Membrane Apical Junction Complex Apical Part Of Cell	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding Protein C-terminus Binding Ion Channel Inhibitor Activity Guanylate Cyclase Inhibitor Activity Protein-membrane Adaptor Activity Ubiquitin-specific Protease Binding	Sodium-independent Organic Anion Transmembrane Transporter Activity
	Biological Process	Ion Transport Water Transport Receptor Guanylyl Cyclase Signaling Pathway Response To Toxic Substance Negative Regulation Of CGMP-mediated Signaling Negative Regulation Of Guanylate Cyclase Activity Protein Localization To Plasma Membrane	Positive Regulation Of Protein Phosphorylation Prostaglandin Transport Sodium-independent Organic Anion Transport Positive Regulation Of NF-kappaB Transcription Factor Activity Transmembrane Transport Transport Across Blood-brain Barrier
Pathways		Intestinal infectious diseases
Drugs
Diseases
GWAS			Acute lymphoblastic leukemia (childhood) ( 22076464) Adult body size ( 32376654) Dementia and core Alzheimer's disease neuropathologic changes ( 25188341) Diastolic blood pressure ( 30224653) DNA methylation (variation) ( 23725790) Estimated glomerular filtration rate reduction (30%) ( 30955190) Gastroesophageal reflux disease ( 27485664) Inattentive symptoms ( 18821565) Neuritic plaque ( 25188341) Obesity-related traits ( 23251661) Orofacial cleft x maternal periconceptional alcohol use interaction (1df) ( 33937227) Post bronchodilator FEV1/FVC ratio ( 26634245) Primary sclerosing cholangitis ( 27992413) Refractive error ( 32231278) Response to iloperidone treatment (QT prolongation) ( 18521091) Smoking initiation ( 24665060)
Interacting Genes		21 interacting genes: ABCC2 ASAP3 CACNA1S CFTR FCER1G GUCY2C NLRX1 NOMO1 PTGIR SLC15A1 SLC15A2 SLC22A3 SLC22A4 SLC22A5 SLC22A9 SLC41A3 SLCO1A2 SLCO1C1 SLCO3A1 SPRYD7 TAS2R8	8 interacting genes: ACAN AQP6 C4orf3 GOLM1 PDZD3 SLC9A3R1 SLC9A3R2 TRARG1
Entrez ID		79849	28232
HPRD ID		06191	07502
Ensembl ID		ENSG00000172367	ENSG00000176463
Uniprot IDs		B0YJ61 Q86UT5	Q9UIG8
PDB IDs		2V90
Enriched GO Terms of Interacting Partners?
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