PDZD3 and ASAP3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		PDZD3	ASAP3
Description		PDZ domain containing 3	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
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GO Annotations	Cellular Component	Cytosol Brush Border Apical Plasma Membrane Apical Junction Complex Apical Part Of Cell	Ruffle Nucleoplasm Cytosol Focal Adhesion Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Protein C-terminus Binding Ion Channel Inhibitor Activity Guanylate Cyclase Inhibitor Activity Protein-membrane Adaptor Activity Ubiquitin-specific Protease Binding	GTPase Activator Activity Protein Binding Metal Ion Binding
	Biological Process	Ion Transport Water Transport Receptor Guanylyl Cyclase Signaling Pathway Response To Toxic Substance Negative Regulation Of CGMP-mediated Signaling Negative Regulation Of Guanylate Cyclase Activity Protein Localization To Plasma Membrane	Cell Migration Positive Regulation Of GTPase Activity Regulation Of Stress Fiber Assembly
Pathways		Intestinal infectious diseases
Drugs
Diseases
GWAS			Cholesterol, total ( 24097068) LDL cholesterol levels ( 32203549) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Total cholesterol levels ( 28334899) Triglyceride levels ( 32203549)
Interacting Genes		21 interacting genes: ABCC2 ASAP3 CACNA1S CFTR FCER1G GUCY2C NLRX1 NOMO1 PTGIR SLC15A1 SLC15A2 SLC22A3 SLC22A4 SLC22A5 SLC22A9 SLC41A3 SLCO1A2 SLCO1C1 SLCO3A1 SPRYD7 TAS2R8	9 interacting genes: ARF6 CRK MTNR1A PDZD3 REL TCF4 TEPSIN TFCP2 UBE3A
Entrez ID		79849	55616
HPRD ID		06191	11662
Ensembl ID		ENSG00000172367	ENSG00000088280
Uniprot IDs		B0YJ61 Q86UT5	A0A024RAB1 B4DRP2 Q8TDY4
PDB IDs		2V90	2B0O 3LVQ 3LVR
Enriched GO Terms of Interacting Partners?
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