PLEKHG4 and SETD5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLEKHG4	SETD5
Description		pleckstrin homology and RhoGEF domain containing G4	SET domain containing 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Euchromatin Nucleus Nucleoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Histone Methyltransferase Activity (H3-K9 Specific) Histone Methyltransferase Activity (H3-K36 Specific)
	Biological Process	Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction	Regulation Of DNA-templated Transcription, Elongation Regulation Of Histone Acetylation Cognition Histone H3-K9 Methylation Regulation Of Synapse Assembly Histone H3-K36 Trimethylation Regulation Of Chromatin Organization
Pathways		RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Blood protein levels ( 29875488 28240269) Body shape index ( 34021172) Heel bone mineral density ( 28869591) High density lipoprotein cholesterol levels ( 33339817) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)	Adult body size ( 32376654) Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Bitter alcoholic beverage consumption ( 31046077) Cerebrospinal fluid clusterin levels ( 26545630) Glucose homeostasis traits ( 25524916) Walking pace ( 33128006)
Interacting Genes		66 interacting genes: A1CF ARHGEF5 ARMC7 BEX2 CCDC120 CCDC187 CDC42 CDKN2C CHIC2 COIL DCUN1D5 DPPA3 DTX2 DUSP13 FAM161A FGD2 GATA3 GCM2 GSTZ1 HCK HOXB9 HOXC8 KRT3 KRT75 MALSU1 MATR3 MDFI METAP1 MSRB3 MTA1 MYEF2 MYOZ1 NATD1 OTX1 PFKFB1 PKP2 PLA2G15 PPP1R32 PRPF18 PRPF31 PSMB1 RHOA RIN1 SAXO1 SETD5 SH2D4A SHISA6 SIX1 SMCP SMG9 TBC1D22B TBX18 TEKT3 TENT5D TFAP2D TFG TRIM55 TRIM63 TSSK3 TTC23 USP2 VPS37C ZCCHC14 ZNF148 ZNF319 ZNF648	11 interacting genes: CALCOCO2 CCDC85B CEP70 DPPA2 KRT40 LDOC1 MTUS2 PLEKHG4 SORBS3 TP53BP2 TRAF2
Entrez ID		25894	55209
HPRD ID		10890	13338
Ensembl ID		ENSG00000196155	ENSG00000168137
Uniprot IDs		A0A024R6X4 Q58EX7	E7EWN3 Q9C0A6
PDB IDs
Enriched GO Terms of Interacting Partners?
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