PLEKHG4 and MALSU1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLEKHG4	MALSU1
Description		pleckstrin homology and RhoGEF domain containing G4	mitochondrial assembly of ribosomal large subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Mitochondrion Cytosol
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding Ribosomal Large Subunit Binding
	Biological Process	Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction	Negative Regulation Of Translation Ribosomal Large Subunit Biogenesis Negative Regulation Of Mitochondrial Translation Negative Regulation Of Ribosome Biogenesis
Pathways		RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Blood protein levels ( 29875488 28240269) Body shape index ( 34021172) Heel bone mineral density ( 28869591) High density lipoprotein cholesterol levels ( 33339817) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)	Iron status biomarkers (transferrin saturation) ( 28334935)
Interacting Genes		66 interacting genes: A1CF ARHGEF5 ARMC7 BEX2 CCDC120 CCDC187 CDC42 CDKN2C CHIC2 COIL DCUN1D5 DPPA3 DTX2 DUSP13 FAM161A FGD2 GATA3 GCM2 GSTZ1 HCK HOXB9 HOXC8 KRT3 KRT75 MALSU1 MATR3 MDFI METAP1 MSRB3 MTA1 MYEF2 MYOZ1 NATD1 OTX1 PFKFB1 PKP2 PLA2G15 PPP1R32 PRPF18 PRPF31 PSMB1 RHOA RIN1 SAXO1 SETD5 SH2D4A SHISA6 SIX1 SMCP SMG9 TBC1D22B TBX18 TEKT3 TENT5D TFAP2D TFG TRIM55 TRIM63 TSSK3 TTC23 USP2 VPS37C ZCCHC14 ZNF148 ZNF319 ZNF648	13 interacting genes: CHMP2B DCTD INCA1 LMO3 MEOX2 MYBPHL NTAQ1 PLEKHG4 SP6 TRIM55 TRIM63 ZFP90 ZNF426
Entrez ID		25894	115416
HPRD ID		10890	12918
Ensembl ID		ENSG00000196155	ENSG00000156928
Uniprot IDs		A0A024R6X4 Q58EX7	Q96EH3
PDB IDs			5OOL 5OOM 7A5H 7A5J
Enriched GO Terms of Interacting Partners?
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