PLEKHG4 and MYEF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLEKHG4	MYEF2
Description		pleckstrin homology and RhoGEF domain containing G4	myelin expression factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus Cytoplasm Post-mRNA Release Spliceosomal Complex Ribonucleoprotein Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Single-stranded DNA Binding RNA Binding MRNA Binding
	Biological Process	Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction	Regulation Of Transcription By RNA Polymerase II Myotube Differentiation Neuron Differentiation Regulation Of MRNA Stability Involved In Response To Oxidative Stress
Pathways		RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Blood protein levels ( 29875488 28240269) Body shape index ( 34021172) Heel bone mineral density ( 28869591) High density lipoprotein cholesterol levels ( 33339817) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)	Skin pigmentation ( 28300201)
Interacting Genes		66 interacting genes: A1CF ARHGEF5 ARMC7 BEX2 CCDC120 CCDC187 CDC42 CDKN2C CHIC2 COIL DCUN1D5 DPPA3 DTX2 DUSP13 FAM161A FGD2 GATA3 GCM2 GSTZ1 HCK HOXB9 HOXC8 KRT3 KRT75 MALSU1 MATR3 MDFI METAP1 MSRB3 MTA1 MYEF2 MYOZ1 NATD1 OTX1 PFKFB1 PKP2 PLA2G15 PPP1R32 PRPF18 PRPF31 PSMB1 RHOA RIN1 SAXO1 SETD5 SH2D4A SHISA6 SIX1 SMCP SMG9 TBC1D22B TBX18 TEKT3 TENT5D TFAP2D TFG TRIM55 TRIM63 TSSK3 TTC23 USP2 VPS37C ZCCHC14 ZNF148 ZNF319 ZNF648	41 interacting genes: COG8 GOLGA2 LNX1 MIR128-2 MIR141 MIR15A MIR17 MIR19B1 MIR19B2 MIR200A MIR20A MIR20B MIR21 MIR221 MIR25 MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR363 MIR429 MIR9-1 MIR9-2 MIR93 MIRLET7A3 MIRLET7B MIRLET7D MIRLET7E MIRLET7F1 MIRLET7G MIRLET7I NFKBID OGT OIP5 PLEKHG4 TEX11 TRAF1 TRIM23 ZRANB1
Entrez ID		25894	50804
HPRD ID		10890	14794
Ensembl ID		ENSG00000196155	ENSG00000104177
Uniprot IDs		A0A024R6X4 Q58EX7	A0A024R5Q6 Q9P2K5
PDB IDs
Enriched GO Terms of Interacting Partners?
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