PLEKHG4 and SAXO1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLEKHG4	SAXO1
Description		pleckstrin homology and RhoGEF domain containing G4	stabilizer of axonemal microtubules 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol	Centriole Cytoskeleton Axonemal Microtubule Motile Cilium Ciliary Basal Body Sperm Flagellum
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Protein Binding Microtubule Binding
	Biological Process	Regulation Of Catalytic Activity Regulation Of Small GTPase Mediated Signal Transduction	Cold Acclimation Cell Projection Organization Microtubule Anchoring Positive Regulation Of Cilium Assembly Protein Stabilization Cellular Response To Cold
Pathways		RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Blood protein levels ( 29875488 28240269) Body shape index ( 34021172) Heel bone mineral density ( 28869591) High density lipoprotein cholesterol levels ( 33339817) Refractive error ( 32231278) Waist circumference adjusted for body mass index ( 34021172)	Cardiovascular event in colchicine-treated recent myocardial infarction (time to event) ( 33560138) Prudent dietary pattern ( 28644415)
Interacting Genes		66 interacting genes: A1CF ARHGEF5 ARMC7 BEX2 CCDC120 CCDC187 CDC42 CDKN2C CHIC2 COIL DCUN1D5 DPPA3 DTX2 DUSP13 FAM161A FGD2 GATA3 GCM2 GSTZ1 HCK HOXB9 HOXC8 KRT3 KRT75 MALSU1 MATR3 MDFI METAP1 MSRB3 MTA1 MYEF2 MYOZ1 NATD1 OTX1 PFKFB1 PKP2 PLA2G15 PPP1R32 PRPF18 PRPF31 PSMB1 RHOA RIN1 SAXO1 SETD5 SH2D4A SHISA6 SIX1 SMCP SMG9 TBC1D22B TBX18 TEKT3 TENT5D TFAP2D TFG TRIM55 TRIM63 TSSK3 TTC23 USP2 VPS37C ZCCHC14 ZNF148 ZNF319 ZNF648	48 interacting genes: ACTN2 AKAP8L ARMC7 BAG4 BEGAIN C19orf54 CARD9 CDKN2D CFAP206 CHERP CPNE7 CRK CYSRT1 FAM124A FBXO17 FHL2 FHL3 FHL5 GLYCTK HEXIM2 HOMER3 HSF2BP IQUB KIR3DX1 KLHL40 LMO1 LMO2 MAPK9 MVP NEK6 NUDT22 OIP5 OSGIN1 PFDN5 PLEKHG4 PM20D2 POLR1C SMARCB1 SORBS3 STK16 TNK1 TRIB3 TRIP6 VPS28 WWOX ZMAT1 ZMYND12 ZMYND19
Entrez ID		25894	158297
HPRD ID		10890	16676
Ensembl ID		ENSG00000196155	ENSG00000155875
Uniprot IDs		A0A024R6X4 Q58EX7	B3KQ57 F6S232 Q5VZT6 Q8IYX7
PDB IDs
Enriched GO Terms of Interacting Partners?
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