PTBP2 - New-wiki

Novel	Interactant Symbol	Name	Associated Pathways Hide	Binding Drugs Hide	Associated Diseases Hide
Novel	GBP1	guanylate binding protein 1	Interferon gamma signaling CASP4 inflammasome assembly Microbial factors inhibit CASP4 activity
Novel	PKN2	protein kinase N2	RHO GTPases activate PKNs RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle RAC1 GTPase cycle High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells	Fostamatinib
	CALCOCO2	calcium binding and coiled-coil domain 2
	EIF5A2	eukaryotic translation initiation factor 5A2	Hypusine synthesis from eIF5A-lysine
	ELAVL1	ELAV like RNA binding protein 1	HuR (ELAVL1) binds and stabilizes mRNA
	GOLGA2	golgin A2	Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
	HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B
	HNRNPC	heterogeneous nuclear ribonucleoprotein C	SUMOylation of RNA binding proteins mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA RHOBTB2 GTPase cycle RHOBTB1 GTPase cycle
	HNRNPD	heterogeneous nuclear ribonucleoprotein D	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA	Artenimol
	ISY1	ISY1 spliceosome associated protein	Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER mRNA Splicing - Major Pathway
	KHDRBS1	KH RNA binding domain containing, signal transduction associated 1	PTK6 Regulates Proteins Involved in RNA Processing
	KHDRBS3	KH RNA binding domain containing, signal transduction associated 3	PTK6 Regulates Proteins Involved in RNA Processing
	KHSRP	KH-type splicing regulatory protein	ATF4 activates genes in response to endoplasmic reticulum stress KSRP (KHSRP) binds and destabilizes mRNA KSRP (KHSRP) binds and destabilizes mRNA	Resveratrol Artenimol
	LINC00624	long intergenic non-protein coding RNA 624
	MAGOH	mago homolog, exon junction complex subunit	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
	MATR3	matrin 3			Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM)
	OGT	O-linked N-acetylglucosamine (GlcNAc) transferase	HATs acetylate histones RIPK1-mediated regulated necrosis Regulation of necroptotic cell death UCH proteinases Formation of WDR5-containing histone-modifying complexes
	PCBP2	poly(rC) binding protein 2	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA Negative regulators of DDX58/IFIH1 signaling SARS-CoV-1 activates/modulates innate immune responses
	PCBP3	poly(rC) binding protein 3
	PRDX4	peroxiredoxin 4	Neutrophil degranulation

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