GSDMB - Wiki-Pi

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17 interactions involving GSDMB - gasdermin B found:

Sort by: Symbol Number of Pathways Number of Drugs Number of Diseases

Novel	Symbol	Description	Pathways Hide	Drugs Hide	Diseases Hide
Novel	CDK12	cyclin dependent kinase 12	TP53 Regulates Transcription of DNA Repair Genes
Novel	CWC25	CWC25 spliceosome associated protein	mRNA Splicing - Major Pathway
Novel	DHRS11	dehydrogenase/reductase 11		Nicotinamide adenine dinucleotide phosphate
Novel	FNDC8	fibronectin type III domain containing 8
Novel	GGNBP2	gametogenetin binding protein 2
Novel	MRM1	mitochondrial rRNA methyltransferase 1	rRNA modification in the mitochondrion
Novel	MYO19	myosin XIX	RHOT2 GTPase cycle RHOT1 GTPase cycle
Novel	NLE1	notchless homolog 1
Novel	SLFN12	schlafen family member 12
	AGT	angiotensinogen	PPARA activates gene expression Metabolism of Angiotensinogen to Angiotensins Metabolism of Angiotensinogen to Angiotensins Peptide ligand-binding receptors Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events	Zinc Copper Sparsentan Zinc acetate	Renal tubular dysgenesis
	APP	amyloid beta precursor protein	Platelet degranulation ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) G alpha (q) signalling events G alpha (i) signalling events Lysosome Vesicle Biogenesis Formyl peptide receptors bind formyl peptides and many other ligands TAK1-dependent IKK and NF-kappa-B activation The NLRP3 inflammasome Advanced glycosylation endproduct receptor signaling Advanced glycosylation endproduct receptor signaling Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models Post-translational protein phosphorylation TRAF6 mediated NF-kB activation Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Purinergic signaling in leishmaniasis infection Amyloid fiber formation	Deferoxamine Aluminium Zinc L-methionine (R)-S-oxide Resveratrol Tromethamine Phenserine Tetrathiomolybdate CAD106 Mito-4509 Edonerpic Dimercaprol Copper Florbetaben (18F) Florbetapir (18F) Flutemetamol (18F) Gantenerumab Aducanumab Zinc acetate Aluminium phosphate Aluminum acetate Zinc chloride Zinc sulfate, unspecified form Lecanemab	Alzheimer's disease (AD)
	CLK1	CDC like kinase 1		Debromohymenialdisine CHGN111 ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate Fostamatinib
	HIVEP1	HIVEP zinc finger 1
	IGFBP2	insulin like growth factor binding protein 2	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
	ORM1	orosomucoid 1	Platelet degranulation Neutrophil degranulation	Amsacrine Lidocaine Progesterone Chlorpromazine Dipyridamole Thalidomide
	PEBP1	phosphatidylethanolamine binding protein 1	MAP2K and MAPK activation Negative regulation of MAPK pathway Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF1 fusions Paradoxical activation of RAF signaling by kinase inactive BRAF Signaling downstream of RAS mutants	Copper
	SERPINA1	serpin family A member 1	Platelet degranulation COPII-mediated vesicle transport Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Cargo concentration in the ER Neutrophil degranulation Post-translational protein phosphorylation	Zinc 2-[3,4-Dihydroxy-2-Hydroxymethyl-5-(2-Hydroxy-Nonyl)-Tetrahydro-Furan-2-Yloxy]-6-Hydroxymethyl-Tetra Hydro-Pyran-3,4,5-Triol Mercaptoethanol Recombinant alpha 1-antitrypsin PPL-100 Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form	Alpha-1-antitrypsin (A1AT) deficiency

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