GSDMB

Gene Name		gasdermin B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm
	Molecular Function
	Biological Process
Pathways
Drugs
Diseases
GWAS		Asthma ( 21804549 20860503) Cervical cancer ( 23817570) Inflammatory bowel disease ( 23128233) Primary biliary cirrhosis ( 23000144 20639880) Ulcerative colitis ( 20228799) White blood cell count ( 21738480)
Protein-protein Interactions		7 interactors: AGT APP HIVEP1 IGFBP2 ORM1 PEBP1 SERPINA1
Entrez ID		55876
HPRD ID		17082
Ensembl ID		ENSG00000073605
Uniprot IDs		Q8TAX9
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Endopeptidase Activity Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Regulation Of Proteolysis Negative Regulation Of Catalytic Activity Negative Regulation Of Cellular Protein Metabolic Process Acute-phase Response Negative Regulation Of Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Tyrosine Kinase Activity Response To Abiotic Stimulus Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Acute Inflammatory Response Regulation Of ERBB Signaling Pathway Developmental Cell Growth Uterine Smooth Muscle Contraction Response To Methanol Angiotensin Mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Secretion By Cell Feeding Behavior Regulation Of Multicellular Organism Growth Response To Estradiol Regulation Of Growth Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Positive Regulation Of Protein Kinase C Activity Synaptic Growth At Neuromuscular Junction Catenin Import Into Nucleus Response To Triglyceride Renal Response To Blood Flow Involved In Circulatory Renin-angiotensin Regulation Of Systemic Arterial Blood Pressure Secretion Cell Activation Cell Growth Angiotensin-mediated Drinking Behavior Smooth Muscle Cell Proliferation Collateral Sprouting In Absence Of Injury Positive Regulation Of NAD(P)H Oxidase Activity Positive Regulation Of Extracellular Matrix Constituent Secretion G-protein Coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger Ovarian Follicle Rupture Regulation Of Renal Output By Angiotensin Response To External Stimulus Response To Chromate Fibroblast Proliferation Astrocyte Activation
Tagcloud ?		17q12 african americans ancestry asthma asthmatic beadchip caribbeans ethnic european explain grasp harbouring heritability humanexome illumina latino latinos loci maf missense missing mthfr parent representing reveals robustly trios variants